METHODS: The present study is analysis of data from the NORDSTEN- SST trial where 437 patients were randomized to one of three mini-invasive surgical methods for lumbar spinal stenosis. The patients underwent MRI examination of the lumbar spine before surgery, and 3 and 24 months after surgery. For all operated segments the dural sac cross-sectional area (DSCA) was measured in mm2. Baseline factors collected included age, gender, BMI and smoking habits. Furthermore, surgical method, index level, number of levels operated, all levels operated on and baseline Schizas grade were also included in the analysis.
RESULTS: 437 patients were enrolled in the NORDSTEN-SST trial, whereof 310 (71%) had MRI at 3 months and 2 years. Mean DSCA at index level was 52.0 mm2 (SD 21.2) at baseline, at 3 months it increased to 117.2 mm2 (SD 43.0) and after 2 years the area was 127.7 mm2 (SD 52.5). Surgical method, level operated on or Schizas did not influence change in DSCA from 3 to 24 months follow-up.
CONCLUSIONS: The spinal canal area after lumbar decompressive surgery for lumbar spinal stenosis increased from baseline to 3 months after surgery and remained thereafter unchanged 2 years postoperatively.
方法:本研究是对NORDSTEN-SST试验数据的分析,其中437例患者被随机分为三种治疗腰椎管狭窄症的微创手术方法之一。患者术前接受腰椎MRI检查,手术后3个月和24个月。对于所有手术节段,测量硬膜囊横截面积(DSCA),单位为mm2。收集的基线因素包括年龄,性别,BMI和吸烟习惯。此外,手术方法,索引级别,操作的级别数,分析中还包括了所有手术水平和基线Schizas级别.
结果:437例患者纳入NORDSTEN-SST试验,其中310例(71%)在3个月和2年时进行了MRI检查。基线时指数水平的平均DSCA为52.0mm2(SD21.2),3个月时面积增加到117.2mm2(SD43.0),2年后面积为127.7mm2(SD52.5)。手术方法,在3~24个月的随访中,对或Schizas操作的水平没有影响DSCA的变化.
结论:腰椎管狭窄症腰椎减压术后椎管面积从基线增加到术后3个月,术后2年保持不变。