PDF(Pubmed)
Abstract：
UNASSIGNED: Gastric varices (GV) with spontaneous portosystemic shunts (SPSS) pose considerable risks and challenges for administering endoscopic cyanoacrylate (CYA) injection. This study aimed to evaluate the efficacy and safety of EUS-guided coil embolization in combination with CYA injection compared to conventional endoscopic CYA injection for managing GV with SPSS.
UNASSIGNED: This retrospective analysis included patients with SPSS treated with either EUS-guided coil embolization in combination with CYA injection or conventional CYA injection for gastric variceal bleeding at Ningbo Medical Center Lihuili Hospital (Zhejiang, China) between January 2018 and March 2023. Patient demographics, procedural details, and follow-up results were reviewed.
UNASSIGNED: The study evaluated 57 patients: 21 in the combined treatment group undergoing EUS-guided coil embolization in combination with CYA injection and 36 in the conventional group receiving conventional endoscopic CYA injection. Both cohorts achieved a 100% technical success rate. The mean volume of CYA used was significantly lower in the combined group (1.64 ± 0.67 mL) than in the conventional group (2.38 ± 0.72 mL; P < 0.001). Early GV rebleeding rates did not differ significantly between the groups; in contrast, the combined treatment group exhibited a considerably lower incidence of late GV rebleeding than the conventional group (4.8% vs 27.8%, P = 0.041).
UNASSIGNED: EUS-guided coil embolization in combination with CYA injection demonstrated superiority over conventional endoscopic CYA injection in reducing late GV rebleeding in treating GV with SPSS.
UNASSIGNED: This retrospective analysis included patients with SPSS treated with either EUS-guided coil embolization in combination with CYA injection or conventional CYA injection for gastric variceal bleeding at Ningbo Medical Center Lihuili Hospital (Zhejiang, China) between January 2018 and March 2023. Patient demographics, procedural details, and follow-up results were reviewed.
UNASSIGNED: The study evaluated 57 patients: 21 in the combined treatment group undergoing EUS-guided coil embolization in combination with CYA injection and 36 in the conventional group receiving conventional endoscopic CYA injection. Both cohorts achieved a 100% technical success rate. The mean volume of CYA used was significantly lower in the combined group (1.64 ± 0.67 mL) than in the conventional group (2.38 ± 0.72 mL; P < 0.001). Early GV rebleeding rates did not differ significantly between the groups; in contrast, the combined treatment group exhibited a considerably lower incidence of late GV rebleeding than the conventional group (4.8% vs 27.8%, P = 0.041).
UNASSIGNED: EUS-guided coil embolization in combination with CYA injection demonstrated superiority over conventional endoscopic CYA injection in reducing late GV rebleeding in treating GV with SPSS.
摘要：
■伴有自发性门体分流(SPSS)的胃静脉曲张(GV)对于给予内窥镜氰基丙烯酸酯(CYA)注射构成相当大的风险和挑战。这项研究旨在评估EUS引导的线圈栓塞与CYA注射联合使用SPSS管理GV的常规内镜CYA注射的有效性和安全性。
■这项回顾性分析包括宁波医学中心李惠利医院（浙江，中国）2018年1月至2023年3月。患者人口统计学，程序细节,并对随访结果进行了综述。
■该研究评估了57例患者：联合治疗组21例接受EUS引导的线圈栓塞联合CYA注射，常规组36例接受常规内镜下CYA注射。这两个团队都取得了100%的技术成功率。联合组使用的CYA平均体积（1.64±0.67mL）明显低于常规组（2.38±0.72mL；P<0.001）。早期GV再出血率在两组之间没有显著差异;相反,联合治疗组晚期GV再出血的发生率明显低于常规组(4.8%vs27.8%,P=0.041)。
■EUS引导的弹簧圈栓塞联合CYA注射在减少SPSS治疗GV的晚期GV再出血方面优于常规内镜下CYA注射。
■这项回顾性分析包括宁波医学中心李惠利医院（浙江，中国）2018年1月至2023年3月。患者人口统计学，程序细节,并对随访结果进行了综述。
■该研究评估了57例患者：联合治疗组21例接受EUS引导的线圈栓塞联合CYA注射，常规组36例接受常规内镜下CYA注射。这两个团队都取得了100%的技术成功率。联合组使用的CYA平均体积（1.64±0.67mL）明显低于常规组（2.38±0.72mL；P<0.001）。早期GV再出血率在两组之间没有显著差异;相反,联合治疗组晚期GV再出血的发生率明显低于常规组(4.8%vs27.8%,P=0.041)。
■EUS引导的弹簧圈栓塞联合CYA注射在减少SPSS治疗GV的晚期GV再出血方面优于常规内镜下CYA注射。
