Home blood pressure and heart rate measurements were obtained by an 81-year old husband and his 74-year old wife in the morning and evening, over the course of an entire month.
Morning and evening systolic blood pressure (129.9 ± 5.5, 125.9 ± 10.2, respectively), and diastolic blood pressure (69.2 ± 4.0, 70.1 ± 5.3) were not different (P > .05), heart rate (61.2 ± 2.9, 69.0 ± 5.5) was higher in the evening (P = .00001) in the husband, while systolic blood pressure (134.7 ± 9.6, 119.0 ± 12.0) and diastolic blood pressure (78.6 ± 5.6, 72.1 ± 7.3) were higher in the morning (P = .00001, P = .00031), and heart rate (62.7 ± 4.7, 68.2 ± 4.6) was higher in the evening (P = .00017) in the wife.
Patient-generated serial home blood pressure and heart rate logs provide essential data for the patients\' management and could potentially be useful in research; circadian variation of blood pressure and heart rate calls for implementation of chronotherapeutic principles for the time of drug administration.
方法:一位81岁的丈夫和他74岁的妻子在早晚进行家庭血压和心率测量,整整一个月的课程。
结果:早晚收缩压(129.9±5.5,125.9±10.2),与舒张压(69.2±4.0,70.1±5.3)比较差异无统计学意义(P>0.05),丈夫晚上心率(61.2±2.9,69.0±5.5)较高(P=0.00001),而早晨收缩压(134.7±9.6,119.0±12.0)和舒张压(78.6±5.6,72.1±7.3)较高(P=0.00001,P=0.00031),妻子晚上心率(62.7±4.7,68.2±4.6)较高(P=0.00017)。
结论:患者生成的连续家庭血压和心率日志为患者的管理提供了必要的数据,可能对研究有用;血压和心率的昼夜节律变化要求在给药时实施计时治疗原则。