Abstract：
OBJECTIVE: In early glottic squamous cell carcinoma, similar results have been described in terms of disease control between transoral laser microsurgery (TLM) and radiation therapy (RT). During the past two decades, several studies compared subjective vocal outcomes of exclusive RT with those of TLM, showing a trend towards improving results for TLM over time. However, the objective differences in terms of spectro-acoustic voice parameters between exclusive RT and TLM have been less frequently investigated. The aim of this systematic review with meta-analysis was to evaluate voice quality after TLM and RT treatment for early glottic carcinoma, based on acoustic analysis parameters including jitter, shimmer, noise to harmonic ratio, fundamental frequency and maximum phonation time.
METHODS: A search of the English published literature was conducted on the Pubmed, Scopus and Cochrane databases following PRISMA guidelines.
RESULTS: A total of 441 titles were retrieved from the search. After full-text screening and application of inclusion/exclusion criteria, 12 articles were included. We found no significant differences between TLM and RT treatment in the considered acoustic analysis parameters, except for Shimmer, with more favorable values reported in the RT group.
CONCLUSIONS: Considering the spread of the disease and expecting an improvement in long-term survival over time, well-designed and multicentric studies involving larger populations with a long-term follow up are mandatory to better assess objective voice outcomes in terms of spectro-acoustic voice parameters.
METHODS: A search of the English published literature was conducted on the Pubmed, Scopus and Cochrane databases following PRISMA guidelines.
RESULTS: A total of 441 titles were retrieved from the search. After full-text screening and application of inclusion/exclusion criteria, 12 articles were included. We found no significant differences between TLM and RT treatment in the considered acoustic analysis parameters, except for Shimmer, with more favorable values reported in the RT group.
CONCLUSIONS: Considering the spread of the disease and expecting an improvement in long-term survival over time, well-designed and multicentric studies involving larger populations with a long-term follow up are mandatory to better assess objective voice outcomes in terms of spectro-acoustic voice parameters.
摘要：
目的：在早期声门鳞状细胞癌，在经口激光显微手术(TLM)和放射治疗(RT)之间的疾病控制方面也描述了类似的结果.在过去的二十年里，几项研究比较了独家RT和TLM的主观声乐结果，显示出随着时间的推移TLM结果改善的趋势。然而,在专用RT和TLM之间的频谱声学语音参数方面的客观差异很少被研究。这项系统评价的目的是评估TLM和RT治疗早期声门型喉癌后的语音质量。基于声学分析参数，包括抖动，shimmer,噪声谐波比，基频和最大发声时间。
方法：在Pubmed，Scopus和Cochrane数据库遵循PRISMA指南。
结果：从搜索中总共检索到441个标题。在全文筛选和应用纳入/排除标准后，包括12篇文章。我们发现TLM和RT治疗在考虑的声学分析参数中没有显着差异，除了Shimmer,在RT组中报告了更有利的值。
结论：考虑到疾病的传播，并期望随着时间的推移，长期生存率得到改善，必须进行设计良好的多中心研究,并对更多人群进行长期随访,以更好地评估频谱声学语音参数方面的客观语音结果.
方法：在Pubmed，Scopus和Cochrane数据库遵循PRISMA指南。
结果：从搜索中总共检索到441个标题。在全文筛选和应用纳入/排除标准后，包括12篇文章。我们发现TLM和RT治疗在考虑的声学分析参数中没有显着差异，除了Shimmer,在RT组中报告了更有利的值。
结论：考虑到疾病的传播，并期望随着时间的推移，长期生存率得到改善，必须进行设计良好的多中心研究,并对更多人群进行长期随访,以更好地评估频谱声学语音参数方面的客观语音结果.
