关键词: Case report Differential diagnoses Follow-up Pericardial effusion Polycystic kidney disease

来  源:   DOI:10.1093/ehjcr/ytae144   PDF(Pubmed)

Abstract:
UNASSIGNED: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disease causing chronic renal failure, with a high incidence of extra-renal manifestations including pericardial effusion.
UNASSIGNED: We present the case of a 41-year-old female, known for ADPKD, who presented to our emergency department with epigastric pain radiating to the interscapular area. Blood exams showed moderate increase in inflammatory markers. Echocardiography revealed a circumferential pericardial effusion of 10 mm. She was put under treatment with colchicine therapy (1 mg b.i.d.) based on a presumptive diagnosis of acute pericarditis with pericardial effusion. She was hospitalized due to increase in pericardial effusion, underwent pericardial drainage, and started prednisone therapy with rapid recovery. We started a close follow-up on a monthly basis, with progressive decrease in pericardial effusion and progressive amelioration in symptoms, although the patient continued to report mild asthenia.
UNASSIGNED: Pericardial effusion and ADPKD are conditions that both require an interdisciplinary discussion for optimal patient care that avoids neglecting pivotal symptoms and avoidable invasive examinations.
摘要:
常染色体显性多囊肾病(ADPKD)是引起慢性肾衰竭的最常见的遗传性疾病,包括心包积液在内的肾外表现发生率很高。
我们介绍一个41岁女性的案例,以ADPKD闻名,他向我们的急诊科就诊,上腹部疼痛放射到肩胛骨间区域。血液检查显示炎症标志物适度增加。超声心动图显示环状心包积液10mm。根据急性心包炎伴心包积液的推定诊断,她接受秋水仙碱治疗(1mgb.i.d.)。她因心包积液增多而住院,接受心包引流,并开始泼尼松治疗,恢复迅速。我们每月开始密切随访,随着心包积液的逐渐减少和症状的逐渐改善,尽管患者继续报告轻度虚弱。
心包积液和ADPKD都需要跨学科的讨论,以实现最佳的患者护理,避免忽略关键症状和可避免的侵入性检查。
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