PDF(Pubmed)
Abstract：
Bacterial infections triggered by patient or healthcare worker contact with surfaces are a major cause of medically acquired infections. By controlling the kinetics of tetrabutyl titanate hydrolysis and condensation during the sol-gel process, it is possible to regulate the content of Ti3+ and oxygen vacancies (OVs) in TiO2, and adjust the associated visible light-induced photocatalytic performance and anti-bacterial adhesion properties. The results have shown that the Ti3+ content in TiO2 was 9.87% at the calcination temperature of the reaction system was 300 °C and pH was 1.0, corresponding to optimal photocatalytic and hydrophilic properties. The formation of a hydrated layer on the superhydrophilic surface provided resistance to bacterial adhesion, preventing cross-contamination on high-touch surfaces. The excellent photocatalytic self-cleaning performance and anti-bacterial adhesion properties can be attributed to synergistic effects associated with the high specific surface area of TiO2 nanoparticles, the mesoporous structure, and the presence of Ti3+ and OVs. The formation of superhydrophilic self-cleaning surfaces under visible light can serve as the basis for the development of a new class of anti-bacterial adhesion materials.
摘要：
由患者或医护人员与表面接触引发的细菌感染是医学获得性感染的主要原因。通过控制钛酸四丁酯在溶胶-凝胶过程中水解和缩合的动力学，可以调节TiO2中Ti3+和氧空位（OVs）的含量，并调节相关的可见光光催化性能和抗细菌粘附性能。结果表明，在反应体系的煅烧温度为300°C，pH为1.0时，TiO2中的Ti3含量为9.87％，对应于最佳的光催化和亲水性能。在超亲水表面上形成水合层提供了对细菌粘附的抵抗力，防止高接触表面的交叉污染。优异的光催化自清洁性能和抗细菌粘附性能可以归因于与TiO2纳米颗粒的高比表面积相关的协同效应，介孔结构，以及Ti3+和OVs的存在。在可见光下形成超亲水自清洁表面可以作为开发新型抗菌粘附材料的基础。
