Abstract：
To investigate the incidence rate of primary brain tumors (PBTs) among Palestinian children over a 6-year interval. This study also aimed to identify the predominant histopathologic types identified in these children.
This retrospective epidemiologic study focused on PBTs in children (<15 years) in Palestine. The data were collected from the registry system at Al-Makassed Hospital in Jerusalem, a prominent referral institution in Palestine and the largest center for PBTs in the region, over a 6 years period from 2018 to 2023.
The incidence rate of PBTs in children (<15 years) was 1.33 per 100,000 person-years, with a 5% mortality rate. Pilocytic astrocytoma was the most common type (24%), followed by medulloblastoma (15.2%) and glioblastoma (6.3%). About one half of the tumors in children were malignant. Headaches were the most common first sign or symptom. About 20% of brain tumors in children were situated within the ventricles, making it the most prevalent location of these tumors, followed by the cerebellum (15.19%) and frontal lobe (11.39%).
This is the first national study in Palestine investigating PBTs in children. The crude incidence rate of primary brain tumors among Palestinian children was lower than the incidence rate in many countries around the world. It is recommended that more research be done on the epidemiology and distribution of PBTs in children in Palestine.
This retrospective epidemiologic study focused on PBTs in children (<15 years) in Palestine. The data were collected from the registry system at Al-Makassed Hospital in Jerusalem, a prominent referral institution in Palestine and the largest center for PBTs in the region, over a 6 years period from 2018 to 2023.
The incidence rate of PBTs in children (<15 years) was 1.33 per 100,000 person-years, with a 5% mortality rate. Pilocytic astrocytoma was the most common type (24%), followed by medulloblastoma (15.2%) and glioblastoma (6.3%). About one half of the tumors in children were malignant. Headaches were the most common first sign or symptom. About 20% of brain tumors in children were situated within the ventricles, making it the most prevalent location of these tumors, followed by the cerebellum (15.19%) and frontal lobe (11.39%).
This is the first national study in Palestine investigating PBTs in children. The crude incidence rate of primary brain tumors among Palestinian children was lower than the incidence rate in many countries around the world. It is recommended that more research be done on the epidemiology and distribution of PBTs in children in Palestine.
摘要：
目的：这项研究的目的是调查6年间隔内巴勒斯坦儿童中原发性脑肿瘤（PBT）的发生率。此外,该研究旨在确定这些儿童的主要组织病理学类型。
方法：这项回顾性流行病学研究的重点是巴勒斯坦儿童（<15岁）的PBT。数据是从耶路撒冷Al-Makassed医院的登记系统收集的，巴勒斯坦著名的转诊机构和该地区最大的PBT中心，从2018年到2023年，为期6年。
结果：儿童（<15岁）的PBT发病率为每100,000人年1.33，死亡率为5%。毛细胞星形细胞瘤是最常见的类型（24％），其次是髓母细胞瘤（15.2%），和胶质母细胞瘤（6.3%）。大约一半的儿童肿瘤是恶性的。头痛是最常见的第一体征或症状。大约20%的儿童脑肿瘤位于脑室内，使其成为这些肿瘤最普遍的位置，其次是小脑(15.19%)，额叶（11.39%）。
结论：这是在巴勒斯坦调查儿童PBT的第一个全国性研究。巴勒斯坦儿童原发性脑肿瘤的粗发病率低于世界许多国家的发病率。建议对巴勒斯坦儿童多溴联苯醚的流行病学和分布进行更多研究。
方法：这项回顾性流行病学研究的重点是巴勒斯坦儿童（<15岁）的PBT。数据是从耶路撒冷Al-Makassed医院的登记系统收集的，巴勒斯坦著名的转诊机构和该地区最大的PBT中心，从2018年到2023年，为期6年。
结果：儿童（<15岁）的PBT发病率为每100,000人年1.33，死亡率为5%。毛细胞星形细胞瘤是最常见的类型（24％），其次是髓母细胞瘤（15.2%），和胶质母细胞瘤（6.3%）。大约一半的儿童肿瘤是恶性的。头痛是最常见的第一体征或症状。大约20%的儿童脑肿瘤位于脑室内，使其成为这些肿瘤最普遍的位置，其次是小脑(15.19%)，额叶（11.39%）。
结论：这是在巴勒斯坦调查儿童PBT的第一个全国性研究。巴勒斯坦儿童原发性脑肿瘤的粗发病率低于世界许多国家的发病率。建议对巴勒斯坦儿童多溴联苯醚的流行病学和分布进行更多研究。
