Abstract：
UNASSIGNED: To explore the efficacy of 0.01% hypochlorous acid (HOCl) in the treatment of hard-to-heal wounds infected by multidrug-resistant Acinetobacter baumannii.
UNASSIGNED: We report a case of hard-to-heal wounds on a patient\'s forearms that were infected by Acinetobacter baumannii. The wounds were treated with 0.01% HOCl. We reviewed the relevant literature and discussed the definition, epidemiology and pathogenesis of hard-to-heal wounds infected by Acinetobacter baumannii. We also explored the safety and efficacy of 0.01% HOCl for the treatment of hard-to-heal wounds infected with Acinetobacter baumannii.
UNASSIGNED: After 3-4 weeks of treatment with 0.01% HOCl, the pain and pruritus of the wounds was gradually alleviated, the infection was controlled and the granulation tissue was fresh. The ulcers also shrank and the nutritional condition of the patient improved. In the fifth week, the skin of the patient\'s right thigh was grafted to repair the wounds, which then healed within 18 days. During the three years of follow-up, the patient had no relapse.
UNASSIGNED: In our case, the 0.01% HOCl seemed to effectively inactivate the bacterial biological biofilm. This helped to promote wound healing, and was non-toxic to the tissues. We consider low-concentration HOCl to be safe and effective for the treatment of hard-to-heal wounds infected with Acinetobacter baumannii.
UNASSIGNED: We report a case of hard-to-heal wounds on a patient\'s forearms that were infected by Acinetobacter baumannii. The wounds were treated with 0.01% HOCl. We reviewed the relevant literature and discussed the definition, epidemiology and pathogenesis of hard-to-heal wounds infected by Acinetobacter baumannii. We also explored the safety and efficacy of 0.01% HOCl for the treatment of hard-to-heal wounds infected with Acinetobacter baumannii.
UNASSIGNED: After 3-4 weeks of treatment with 0.01% HOCl, the pain and pruritus of the wounds was gradually alleviated, the infection was controlled and the granulation tissue was fresh. The ulcers also shrank and the nutritional condition of the patient improved. In the fifth week, the skin of the patient\'s right thigh was grafted to repair the wounds, which then healed within 18 days. During the three years of follow-up, the patient had no relapse.
UNASSIGNED: In our case, the 0.01% HOCl seemed to effectively inactivate the bacterial biological biofilm. This helped to promote wound healing, and was non-toxic to the tissues. We consider low-concentration HOCl to be safe and effective for the treatment of hard-to-heal wounds infected with Acinetobacter baumannii.
摘要：
■探讨0.01％次氯酸（HOCl）治疗多重耐药鲍曼不动杆菌感染的难以愈合伤口的疗效。
■我们报告一例患者前臂难以愈合的伤口感染鲍曼不动杆菌。用0.01%HOCl处理伤口。我们回顾了相关文献，讨论了定义，鲍曼不动杆菌感染难以愈合伤口的流行病学和发病机制。我们还探讨了0.01％HOCl治疗鲍曼不动杆菌感染的难以愈合伤口的安全性和有效性。
■用0.01%HOCl治疗3-4周后，伤口的疼痛和瘙痒逐渐减轻，感染得到控制，肉芽组织新鲜。溃疡也缩小，患者的营养状况得到改善。在第五周，病人右大腿的皮肤被移植来修复伤口，然后在18天内痊愈。在三年的随访中，患者没有复发。
■在我们的例子中，0.01%HOCl似乎有效地使细菌生物生物膜失活。这有助于促进伤口愈合，对组织无毒。我们认为低浓度HOCl对于治疗鲍曼不动杆菌感染的难以愈合的伤口是安全有效的。
■我们报告一例患者前臂难以愈合的伤口感染鲍曼不动杆菌。用0.01%HOCl处理伤口。我们回顾了相关文献，讨论了定义，鲍曼不动杆菌感染难以愈合伤口的流行病学和发病机制。我们还探讨了0.01％HOCl治疗鲍曼不动杆菌感染的难以愈合伤口的安全性和有效性。
■用0.01%HOCl治疗3-4周后，伤口的疼痛和瘙痒逐渐减轻，感染得到控制，肉芽组织新鲜。溃疡也缩小，患者的营养状况得到改善。在第五周，病人右大腿的皮肤被移植来修复伤口，然后在18天内痊愈。在三年的随访中，患者没有复发。
■在我们的例子中，0.01%HOCl似乎有效地使细菌生物生物膜失活。这有助于促进伤口愈合，对组织无毒。我们认为低浓度HOCl对于治疗鲍曼不动杆菌感染的难以愈合的伤口是安全有效的。
