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Abstract：
UNASSIGNED: This study aims to investigate the relationship between serum vitamin D, total IgE levels and chronic spontaneous urticaria (CSU).
UNASSIGNED: We collected data from 101 patients with chronic spontaneous urticaria (experimental group) and 115 healthy normal subjects (control group) in the same period of physical examination.
UNASSIGNED: The results showed that the number of deficient and absolute deficient 25-hydroxyvitamin D in the experimental group was significantly lower than in the control group (P < 0.05). Pearson correlation analysis showed that the activity score of CSU patients was negatively correlated with serum vitamin D (r = -0.2278, P = 0.0220) and positively correlated with IgE (r = 0.2078, P = 0.0380). It was observed that serum vitamin D in CSU patients was negatively correlated with their activity (r = -0.2278, P = 0.0220) and positively correlated with age (r = 0.2675, P = 0.0069). The Point-biserial correlation analysis revealed that gender was positively correlated with serum vitamin D (Pearson correlation coefficient = 0.286, P = 0.004) and UAS score (Pearson correlation coefficient = 0.273, P = 0.006). Ordinal logistic regression analysis showed that only serum vitamin D was correlated to activity scores (P = 0.008). In addition to activity scores, age (P = 0.005) and gender (P = 0.04) were correlated to serum vitamin D.
UNASSIGNED: The activity score of CSU patients was negatively correlated with serum vitamin D and positively correlated with IgE. Serum vitamin D in CSU patients was negatively correlated with activity score and disease duration and positively correlated with age and gender.
UNASSIGNED: We collected data from 101 patients with chronic spontaneous urticaria (experimental group) and 115 healthy normal subjects (control group) in the same period of physical examination.
UNASSIGNED: The results showed that the number of deficient and absolute deficient 25-hydroxyvitamin D in the experimental group was significantly lower than in the control group (P < 0.05). Pearson correlation analysis showed that the activity score of CSU patients was negatively correlated with serum vitamin D (r = -0.2278, P = 0.0220) and positively correlated with IgE (r = 0.2078, P = 0.0380). It was observed that serum vitamin D in CSU patients was negatively correlated with their activity (r = -0.2278, P = 0.0220) and positively correlated with age (r = 0.2675, P = 0.0069). The Point-biserial correlation analysis revealed that gender was positively correlated with serum vitamin D (Pearson correlation coefficient = 0.286, P = 0.004) and UAS score (Pearson correlation coefficient = 0.273, P = 0.006). Ordinal logistic regression analysis showed that only serum vitamin D was correlated to activity scores (P = 0.008). In addition to activity scores, age (P = 0.005) and gender (P = 0.04) were correlated to serum vitamin D.
UNASSIGNED: The activity score of CSU patients was negatively correlated with serum vitamin D and positively correlated with IgE. Serum vitamin D in CSU patients was negatively correlated with activity score and disease duration and positively correlated with age and gender.
摘要：
■本研究旨在探讨血清维生素D，总IgE水平和慢性自发性荨麻疹（CSU）。
■我们收集了同期体检的101例慢性自发性荨麻疹患者（实验组）和115例健康正常人（对照组）的数据。
■结果显示，实验组缺乏和绝对缺乏25-羟基维生素D的数量明显低于对照组（P<0.05）。Pearson相关分析显示,CSU患者活动评分与血清维生素D呈负相关(r=-0.2278,P=0.0220),与IgE呈正相关(r=0.2078,P=0.0380)。CSU患者血清维生素D与活动度呈负相关(r=-0.2278,P=0.0220),与年龄呈正相关(r=0.2675,P=0.0069)。点相关分析显示，性别与血清维生素D（Pearson相关系数=0.286，P=0.004）和UAS评分（Pearson相关系数=0.273，P=0.006）呈正相关。有序logistic回归分析显示，只有血清维生素D与活动评分相关（P=0.008）。除了活动得分，年龄（P=0.005）和性别（P=0.04）与血清维生素D相关。
■CSU患者的活动评分与血清维生素D呈负相关，与IgE呈正相关。CSU患者血清维生素D与活动评分、病程呈负相关,与年龄、性别呈正相关。
■我们收集了同期体检的101例慢性自发性荨麻疹患者（实验组）和115例健康正常人（对照组）的数据。
■结果显示，实验组缺乏和绝对缺乏25-羟基维生素D的数量明显低于对照组（P<0.05）。Pearson相关分析显示,CSU患者活动评分与血清维生素D呈负相关(r=-0.2278,P=0.0220),与IgE呈正相关(r=0.2078,P=0.0380)。CSU患者血清维生素D与活动度呈负相关(r=-0.2278,P=0.0220),与年龄呈正相关(r=0.2675,P=0.0069)。点相关分析显示，性别与血清维生素D（Pearson相关系数=0.286，P=0.004）和UAS评分（Pearson相关系数=0.273，P=0.006）呈正相关。有序logistic回归分析显示，只有血清维生素D与活动评分相关（P=0.008）。除了活动得分，年龄（P=0.005）和性别（P=0.04）与血清维生素D相关。
■CSU患者的活动评分与血清维生素D呈负相关，与IgE呈正相关。CSU患者血清维生素D与活动评分、病程呈负相关,与年龄、性别呈正相关。
