{Reference Type}: Journal Article
{Title}: The Correlation between Serum Vitamin D and Total IgE Levels and Chronic Spontaneous Urticaria among Chinese Population: A Retrospective Study.
{Author}: Liu J;Wang F;Cao H;Wang Y;Liang F;Jiang S;Zhang H;Luo J;
{Journal}: Indian J Dermatol
{Volume}: 69
{Issue}: 1
{Year}: 2024 Jan-Feb
{Factor}: 1.757
{DOI}: 10.4103/ijd.ijd_634_22
{Abstract}: <B>UNASSIGNED: </B>This study aims to investigate the relationship between serum vitamin D, total IgE levels and chronic spontaneous urticaria (CSU).<BR><B>UNASSIGNED: </B>We collected data from 101 patients with chronic spontaneous urticaria (experimental group) and 115 healthy normal subjects (control group) in the same period of physical examination.<BR><B>UNASSIGNED: </B>The results showed that the number of deficient and absolute deficient 25-hydroxyvitamin D in the experimental group was significantly lower than in the control group (P < 0.05). Pearson correlation analysis showed that the activity score of CSU patients was negatively correlated with serum vitamin D (r = -0.2278, P = 0.0220) and positively correlated with IgE (r = 0.2078, P = 0.0380). It was observed that serum vitamin D in CSU patients was negatively correlated with their activity (r = -0.2278, P = 0.0220) and positively correlated with age (r = 0.2675, P = 0.0069). The Point-biserial correlation analysis revealed that gender was positively correlated with serum vitamin D (Pearson correlation coefficient = 0.286, P = 0.004) and UAS score (Pearson correlation coefficient = 0.273, P = 0.006). Ordinal logistic regression analysis showed that only serum vitamin D was correlated to activity scores (P = 0.008). In addition to activity scores, age (P = 0.005) and gender (P = 0.04) were correlated to serum vitamin D.<BR><B>UNASSIGNED: </B>The activity score of CSU patients was negatively correlated with serum vitamin D and positively correlated with IgE. Serum vitamin D in CSU patients was negatively correlated with activity score and disease duration and positively correlated with age and gender.