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Abstract：
BACKGROUND: In fetal surgery, successful pain management is crucial for postoperative mobilization, prophylaxis of contractions, and fast recovery. This study analyzed patient\'s pain experience after open fetal spina bifida (fSB) repair in comparison to pain scores after the subsequent Caesarean section (C-section).
METHODS: Data were collected with a questionnaire given to 91 women, who had fSB repair and then C-section at our center between 2019 and 2022. It comprised 12 questions covering different aspects of pain experience and satisfaction with pain therapy and was answered by 67 women after fSB repair and 53 after C-section. Postoperative pain was rated on a Likert scale from 0 (slight/rarely) to 100 (strongest/always). Outcomes after fSB repair were compared to those after C-section. Additionally, subgroup analysis compared outcomes of women with different pain levels (group 1-5) after fSB repair.
RESULTS: Compared to women after C-section women after fSB repair reported significantly higher maximum pain scores (MPS) (p = 0.03), higher sleep disturbance due to pain (p = 0.03), and sedation rates (p = 0.001) as side effect from pain therapy. No differences were found regarding feelings of insecurity (p = 0.20) or helplessness (p = 0.40), as well as involvement in (p = 0.3) and satisfaction with pain therapy (p = 0.5). Subgroup analysis revealed that women with higher MPS after fSB repair were significantly more often non-Caucasians (p = 0.003) and more often affected by pain while lying in bed (p = 0.007) and during mobilization (p = 0.005). Additionally, they reported higher rates of dizziness (p = 0.02) and lower satisfaction rates with pain therapy (p = 0.03). Postoperative complication rate did not differ among groups.
CONCLUSIONS: Although women after fSB repair reported higher MPS compared to after C-section, the current pain management was generally perceived as satisfactory.
METHODS: Data were collected with a questionnaire given to 91 women, who had fSB repair and then C-section at our center between 2019 and 2022. It comprised 12 questions covering different aspects of pain experience and satisfaction with pain therapy and was answered by 67 women after fSB repair and 53 after C-section. Postoperative pain was rated on a Likert scale from 0 (slight/rarely) to 100 (strongest/always). Outcomes after fSB repair were compared to those after C-section. Additionally, subgroup analysis compared outcomes of women with different pain levels (group 1-5) after fSB repair.
RESULTS: Compared to women after C-section women after fSB repair reported significantly higher maximum pain scores (MPS) (p = 0.03), higher sleep disturbance due to pain (p = 0.03), and sedation rates (p = 0.001) as side effect from pain therapy. No differences were found regarding feelings of insecurity (p = 0.20) or helplessness (p = 0.40), as well as involvement in (p = 0.3) and satisfaction with pain therapy (p = 0.5). Subgroup analysis revealed that women with higher MPS after fSB repair were significantly more often non-Caucasians (p = 0.003) and more often affected by pain while lying in bed (p = 0.007) and during mobilization (p = 0.005). Additionally, they reported higher rates of dizziness (p = 0.02) and lower satisfaction rates with pain therapy (p = 0.03). Postoperative complication rate did not differ among groups.
CONCLUSIONS: Although women after fSB repair reported higher MPS compared to after C-section, the current pain management was generally perceived as satisfactory.
摘要：
背景：在胎儿手术中，成功的疼痛管理对于术后动员至关重要，预防宫缩，和快速恢复。本研究分析了开放式胎儿脊柱裂（fSB）修复后患者的疼痛经历，并与随后的剖腹产（剖腹产）后的疼痛评分进行比较。
方法：通过对91名女性进行问卷调查来收集数据，他们在2019年至2022年期间在我们的中心进行了fSB维修，然后进行了剖腹产。它包括12个问题，涵盖疼痛体验和疼痛治疗满意度的不同方面，在fSB修复后由67名女性回答，在剖腹产后由53名女性回答。术后疼痛在Likert量表上从0（轻微/很少）到100（最强/总是）进行评分。将fSB修复后的结果与剖腹产后的结果进行比较。此外,亚组分析比较了不同疼痛程度女性(第1-5组)fSB修复后的结局.
结果：与剖腹产后的女性相比，fSB修复后的女性报告的最大疼痛评分（MPS）明显更高（p=0.03），更高的睡眠障碍由于疼痛（p=0.03），和镇静率（p=0.001）作为疼痛治疗的副作用。在不安全感（p=0.20）或无助感（p=0.40）方面没有发现差异，以及参与（p=0.3）和对疼痛治疗的满意度（p=0.5）。亚组分析显示，fSB修复后MPS较高的女性非高加索人（p=0.003），并且在躺在床上（p=0.007）和动员期间（p=0.005）更容易受到疼痛的影响。此外，他们报告了较高的头晕率（p=0.02）和较低的满意度疼痛治疗（p=0.03）。术后并发症发生率组间无差异。
结论：尽管fSB修复后的女性报告的MPS高于剖腹产后，目前的疼痛管理被普遍认为令人满意.
方法：通过对91名女性进行问卷调查来收集数据，他们在2019年至2022年期间在我们的中心进行了fSB维修，然后进行了剖腹产。它包括12个问题，涵盖疼痛体验和疼痛治疗满意度的不同方面，在fSB修复后由67名女性回答，在剖腹产后由53名女性回答。术后疼痛在Likert量表上从0（轻微/很少）到100（最强/总是）进行评分。将fSB修复后的结果与剖腹产后的结果进行比较。此外,亚组分析比较了不同疼痛程度女性(第1-5组)fSB修复后的结局.
结果：与剖腹产后的女性相比，fSB修复后的女性报告的最大疼痛评分（MPS）明显更高（p=0.03），更高的睡眠障碍由于疼痛（p=0.03），和镇静率（p=0.001）作为疼痛治疗的副作用。在不安全感（p=0.20）或无助感（p=0.40）方面没有发现差异，以及参与（p=0.3）和对疼痛治疗的满意度（p=0.5）。亚组分析显示，fSB修复后MPS较高的女性非高加索人（p=0.003），并且在躺在床上（p=0.007）和动员期间（p=0.005）更容易受到疼痛的影响。此外，他们报告了较高的头晕率（p=0.02）和较低的满意度疼痛治疗（p=0.03）。术后并发症发生率组间无差异。
结论：尽管fSB修复后的女性报告的MPS高于剖腹产后，目前的疼痛管理被普遍认为令人满意.
