Abstract：
UNASSIGNED: Stroke is the second leading cause of death and the leading cause of disability worldwide. However, how the prevalence of stroke varies across the world is uncertain.
UNASSIGNED: The aim of this study was to analyze temporal trends of prevalence for stroke, including ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) at the global, regional, and national levels.
UNASSIGNED: The age-standardized prevalence rates (ASPR) of stroke, IS, ICH, and SAH, along with their corresponding 95% uncertainty intervals (UI), were derived from data in the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This provides estimates for the burden of 369 diseases and injuries globally in 2019, as well as their temporal trends over the past 30 years. Joinpoint regression analysis was used to analyze the 1990-2019 temporal trends by calculating the annual percentage change (APC) and average annual percentage change (AAPC), as well as their 95% confidence interval (CI).
UNASSIGNED: In 2019, the global ASPR of stroke was 1240.263 per 100,000 population (95% UI: 1139.711 to 1352.987), with ASPRs generally lower in Europe compared to other regions. Over the period from 1990 to 2019, a significant global decrease in ASPR was observed for stroke (AAPC -0.200, 95% CI: -0.215 to -0.183), IS (AAPC -0.059%, 95% CI: -0.077 to -0.043), SAH (AAPC -0.476, 95% CI: -0.483 to -0.469), and ICH (AAPC -0.626, 95% CI: -0.642 to -0.611). The trends of ASPR of stroke, IS, SAH, and ICH varied significantly across 204 countries and territories.
UNASSIGNED: Our findings highlight significant global disparities in stroke prevalence, emphasizing the need for ongoing monitoring and intensified efforts in developing regions to reduce the global burden of stroke.
UNASSIGNED: The aim of this study was to analyze temporal trends of prevalence for stroke, including ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) at the global, regional, and national levels.
UNASSIGNED: The age-standardized prevalence rates (ASPR) of stroke, IS, ICH, and SAH, along with their corresponding 95% uncertainty intervals (UI), were derived from data in the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This provides estimates for the burden of 369 diseases and injuries globally in 2019, as well as their temporal trends over the past 30 years. Joinpoint regression analysis was used to analyze the 1990-2019 temporal trends by calculating the annual percentage change (APC) and average annual percentage change (AAPC), as well as their 95% confidence interval (CI).
UNASSIGNED: In 2019, the global ASPR of stroke was 1240.263 per 100,000 population (95% UI: 1139.711 to 1352.987), with ASPRs generally lower in Europe compared to other regions. Over the period from 1990 to 2019, a significant global decrease in ASPR was observed for stroke (AAPC -0.200, 95% CI: -0.215 to -0.183), IS (AAPC -0.059%, 95% CI: -0.077 to -0.043), SAH (AAPC -0.476, 95% CI: -0.483 to -0.469), and ICH (AAPC -0.626, 95% CI: -0.642 to -0.611). The trends of ASPR of stroke, IS, SAH, and ICH varied significantly across 204 countries and territories.
UNASSIGNED: Our findings highlight significant global disparities in stroke prevalence, emphasizing the need for ongoing monitoring and intensified efforts in developing regions to reduce the global burden of stroke.
摘要：
中风是全球第二大死亡原因和主要致残原因。然而,中风的患病率在世界范围内如何变化尚不确定.
■这项研究的目的是分析中风患病率的时间趋势，包括缺血性卒中（IS），脑出血（ICH），和蛛网膜下腔出血（SAH）在全球，区域,和国家层面。
■中风的年龄标准化患病率（ASPR），IS,ICH,和SAH,以及它们相应的95%不确定度区间(UI)，来自全球疾病负担的数据，受伤,和风险因素研究（GBD）2019年。这提供了2019年全球369种疾病和伤害负担的估计，以及过去30年的时间趋势。采用Joinpoint回归分析，通过计算年百分比变化（APC）和平均APC（AAPC）来分析1990-2019年的时间趋势，以及他们的95%置信区间(CI)。
■2019年，中风的全球ASPR为每100,000人口1240.263（95％UI：1139.711至1352.987），与其他地区相比，欧洲的ASPR普遍较低。在1990年至2019年期间，观察到卒中的ASPR在全球范围内显着下降（AAPC-0.200，95％CI：-0.215至-0.183），IS（AAPC-0.059%，95%CI：-0.077至-0.043），SAH（AAPC-0.476，95%CI：-0.483至-0.469），和ICH（AAPC-0.626，95%CI：-0.642至-0.611）。中风ASPR的发展趋势，IS,SAH和ICH在204个国家和地区差异很大。
■我们的研究结果强调了卒中患病率的显著全球差异，强调发展中地区需要持续监测和加强努力，以减轻全球卒中负担。
■这项研究的目的是分析中风患病率的时间趋势，包括缺血性卒中（IS），脑出血（ICH），和蛛网膜下腔出血（SAH）在全球，区域,和国家层面。
■中风的年龄标准化患病率（ASPR），IS,ICH,和SAH,以及它们相应的95%不确定度区间(UI)，来自全球疾病负担的数据，受伤,和风险因素研究（GBD）2019年。这提供了2019年全球369种疾病和伤害负担的估计，以及过去30年的时间趋势。采用Joinpoint回归分析，通过计算年百分比变化（APC）和平均APC（AAPC）来分析1990-2019年的时间趋势，以及他们的95%置信区间(CI)。
■2019年，中风的全球ASPR为每100,000人口1240.263（95％UI：1139.711至1352.987），与其他地区相比，欧洲的ASPR普遍较低。在1990年至2019年期间，观察到卒中的ASPR在全球范围内显着下降（AAPC-0.200，95％CI：-0.215至-0.183），IS（AAPC-0.059%，95%CI：-0.077至-0.043），SAH（AAPC-0.476，95%CI：-0.483至-0.469），和ICH（AAPC-0.626，95%CI：-0.642至-0.611）。中风ASPR的发展趋势，IS,SAH和ICH在204个国家和地区差异很大。
■我们的研究结果强调了卒中患病率的显著全球差异，强调发展中地区需要持续监测和加强努力，以减轻全球卒中负担。
