Abstract：
UNASSIGNED: Epilepsy is a neurological disorder characterized by recurrent seizures. We aimed to investigate the association between the percentage of dietary carbohydrate intake (DCI) and epilepsy prevalence among American adults.
UNASSIGNED: We analyzed the data from 9,584 adults aged 20-80 years who participated in the National Health and Nutrition Examination Survey from 2013 to 2018. Logistic regression was applied to explore the association between the percentage of DCI and epilepsy prevalence.
UNASSIGNED: A total of 146 (1.5%) individuals with epilepsy were enrolled in this study. The average age of the participants was 56.4 years, and 5,454 (56.9%) individuals were female. A high DCI was associated with an increased prevalence of epilepsy (odds ratio [OR], 4.56; 95% confidence interval [CI], 1.11-18.69; P = 0.035) after adjusting for age, sex, marital status, race/ethnicity, educational level, family income, body mass index, smoking status, drinking status, hypertension, diabetes, and cardiovascular disease. Stratified analyses indicated a positive correlation between DCI and epilepsy prevalence in adults with different characteristics. Compared with individuals in quartile 1 of DCI (<40.5%), those in quartile 4 (>55.4%) had an adjusted OR for epilepsy of 1.72 (95% CI, 1.09-2.73, P = 0.02, P for trend = 0.012).
UNASSIGNED: A high percentage of DCI was associated with an increased prevalence of epilepsy. The risk of epilepsy increased 3.5-fold with a 1% increase in DCI. These results suggest an important role of DCI in the dietary management of epilepsy.
UNASSIGNED: We analyzed the data from 9,584 adults aged 20-80 years who participated in the National Health and Nutrition Examination Survey from 2013 to 2018. Logistic regression was applied to explore the association between the percentage of DCI and epilepsy prevalence.
UNASSIGNED: A total of 146 (1.5%) individuals with epilepsy were enrolled in this study. The average age of the participants was 56.4 years, and 5,454 (56.9%) individuals were female. A high DCI was associated with an increased prevalence of epilepsy (odds ratio [OR], 4.56; 95% confidence interval [CI], 1.11-18.69; P = 0.035) after adjusting for age, sex, marital status, race/ethnicity, educational level, family income, body mass index, smoking status, drinking status, hypertension, diabetes, and cardiovascular disease. Stratified analyses indicated a positive correlation between DCI and epilepsy prevalence in adults with different characteristics. Compared with individuals in quartile 1 of DCI (<40.5%), those in quartile 4 (>55.4%) had an adjusted OR for epilepsy of 1.72 (95% CI, 1.09-2.73, P = 0.02, P for trend = 0.012).
UNASSIGNED: A high percentage of DCI was associated with an increased prevalence of epilepsy. The risk of epilepsy increased 3.5-fold with a 1% increase in DCI. These results suggest an important role of DCI in the dietary management of epilepsy.
摘要：
■癫痫是一种以反复发作为特征的神经系统疾病。我们旨在调查美国成年人膳食碳水化合物摄入量（DCI）百分比与癫痫患病率之间的关系。
■我们分析了2013年至2018年参加全国健康和营养检查调查的9,584名20-80岁成年人的数据。应用Logistic回归分析DCI比例与癫痫患病率的相关性。
■本研究共纳入146例（1.5%）癫痫患者。参与者的平均年龄为56.4岁，5,454人(56.9%)为女性。高DCI与癫痫患病率增加相关(比值比[OR]，4.56；95%置信区间[CI]，1.11-18.69；P=0.035）调整年龄后，性别,婚姻状况,种族/民族,教育水平,家庭收入,身体质量指数,吸烟状况,饮酒状况,高血压,糖尿病,和心血管疾病。分层分析表明，在具有不同特征的成年人中，DCI与癫痫患病率之间存在正相关。与DCI四分位数1的个体相比(<40.5%)，四分位数4(>55.4%)的癫痫校正OR为1.72(95%CI,1.09-2.73,P=0.02,趋势P=0.012).
■高比例的DCI与癫痫患病率增加有关。癫痫的风险增加了3.5倍，DCI增加了1％。这些结果表明DCI在癫痫的饮食管理中具有重要作用。
■我们分析了2013年至2018年参加全国健康和营养检查调查的9,584名20-80岁成年人的数据。应用Logistic回归分析DCI比例与癫痫患病率的相关性。
■本研究共纳入146例（1.5%）癫痫患者。参与者的平均年龄为56.4岁，5,454人(56.9%)为女性。高DCI与癫痫患病率增加相关(比值比[OR]，4.56；95%置信区间[CI]，1.11-18.69；P=0.035）调整年龄后，性别,婚姻状况,种族/民族,教育水平,家庭收入,身体质量指数,吸烟状况,饮酒状况,高血压,糖尿病,和心血管疾病。分层分析表明，在具有不同特征的成年人中，DCI与癫痫患病率之间存在正相关。与DCI四分位数1的个体相比(<40.5%)，四分位数4(>55.4%)的癫痫校正OR为1.72(95%CI,1.09-2.73,P=0.02,趋势P=0.012).
■高比例的DCI与癫痫患病率增加有关。癫痫的风险增加了3.5倍，DCI增加了1％。这些结果表明DCI在癫痫的饮食管理中具有重要作用。
