PDF(Pubmed)
Abstract：
Striae distensae or stretch marks are a common complaint among women and can be distressing. The present study aimed to assess the efficacy of a mixture of low molecular weight hyaluronic acid and six amino acids when applied with a specific intradermal injection technique known as intra-mural fluid technique. A clinical study was carried out in 32 patients (with a dropout rate by 9.4%) with striae distensae alba (SA) in one or more of the following anatomical areas: breast, abdomen, inner thigh, trochanteric area, gluteal area, posterior supra-iliac area, and lumbar area. Product efficacy was assessed by the investigator using the Global Aesthetic Improvement Scale, while a Likert scale was used to evaluate to score the treatment tolerability and a QoL stretch marks questionnaire was used to investigate the patients\' self-body image. The treatment was effective in improving the appearance of SA fifteen days after the second treatment and 6 months after the first treatment (and after a total of 4 treatments). The product efficacy and tolerability were also perceived by the patients during each treatment session. Our results suggest that the test treatment is a valid treatment option to decrease the appearance of SA. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors https://www.springer.com/00266.
摘要：
纹纹或妊娠纹是女性常见的主诉，可能令人痛苦。本研究旨在评估低分子量透明质酸和六种氨基酸的混合物在使用称为壁内流体技术的特定皮内注射技术时的功效。在以下一个或多个解剖区域中，对32例（脱失率9.4％）的白纹（SA）患者进行了临床研究：乳腺，腹部，大腿内侧,转子区,臀区,后髂上区,和腰部区域。研究者使用全球美学改善量表评估产品疗效，使用Likert量表对治疗耐受性进行评分，并使用QoL妊娠纹问卷调查患者的自我体象。该治疗在第二次治疗后15天和第一次治疗后6个月(和总共4次治疗后)有效改善SA的外观。在每次治疗期间,患者也感知到产品功效和耐受性。我们的结果表明，测试治疗是减少SA外观的有效治疗选择。证据级别IV：本期刊要求作者为每篇文章指定一个级别的证据。对于这些循证医学评级的完整描述，请参阅目录或对作者的在线说明https://www。springer.com/00266.
