PDF(Pubmed)
Abstract：
We present a case involving a 60-year-old man with subacute delirium characterized by challenging attention shifts and obstinate behavior, contrasting with his usual mild-mannered personality. The patient developed pneumonia and a urinary tract infection following the onset of subacute delirium. Despite exhaustive investigations, the cause remained elusive until cerebrospinal fluid analysis revealed Tau positivity. Our overview suggests neurodegenerative diseases as the primary cause, rather than infectious or autoimmune factors. The case underscores a significant association between Tau and delirium superimposed on dementia, offering guidance to clinicians managing such patients.
摘要：
我们提出了一个涉及一名60岁的亚急性谵妄患者的病例，其特征是具有挑战性的注意力转移和顽固的行为。与他一贯温和的性格形成鲜明对比。患者在亚急性谵妄发作后出现肺炎和尿路感染。尽管进行了详尽的调查，在脑脊液分析显示Tau阳性之前，原因仍然难以捉摸。我们的概述表明神经退行性疾病是主要原因，而不是感染或自身免疫因素。该病例强调了Tau与痴呆症叠加的谵妄之间的显着关联，为管理此类患者的临床医生提供指导。
