PDF(Pubmed)
Abstract：
Tianeptine is an atypical tricyclic antidepressant approved for the treatment of major depressive disorder in some European, Asian, and Latin countries. Along with its serotonergic properties, tianeptine also acts as a full agonist at the mu-opioid receptor, creating sensations of euphoric highs and significant risks of addiction and withdrawal. For this reason, along with increased reports of adverse effects and fatalities, tianeptine has not been approved in the US. Despite this, tianeptine continues to be accessible through unregulated online stores and small retailers under street names such as Zaza, Tia, Tianna, \'gas-station dope\', and a product not mentioned in the literature previously: Neptune\'s Fix Elixir. In this report, we discuss the case of a 34-year-old male who presented to the ED via EMS after being found unresponsive secondary to the ingestion of Neptune\'s Fix Elixir, whose main active ingredient is tianeptine.
摘要：
Tianeptine是一种非典型的三环抗抑郁药，在某些欧洲被批准用于治疗重度抑郁症，亚洲人,和拉丁美洲国家。除了它的血清素能特性，tianeptine还可以作为μ阿片受体的完全激动剂，产生欣快感和成瘾和戒断的重大风险。出于这个原因,随着不良反应和死亡报告的增加，tianeptine尚未在美国获得批准。尽管如此,tianeptine仍然可以通过不受监管的在线商店和小型零售商以Zaza等街道名称访问，Tia,Tianna,\'加油站涂料\',和之前文献中没有提到的产品：海王星的修复药剂。在这份报告中,我们讨论了一名34岁男性的案例，该男性在摄入海王星的FixElixir后被发现无反应后，通过EMS提交给ED，其主要活性成分是噻奈普汀。
