Abstract：
Attempts were made to improve the efficacy of PCR amplified immunoassay (I-PCR) for diagnosing abdominal TB cases by utilizing the gold nanoparticle (AuNP)-based I-PCR, where AuNPs were functionalized with detection antibodies/oligonucleotides that exhibited 84.3% sensitivity and 95.1% specificity. This assay would improve the ongoing algorithms used in abdominal TB diagnosis.
摘要：
尝试通过利用基于金纳米颗粒（AuNP）的I-PCR来提高PCR扩增免疫测定（I-PCR）诊断腹部结核病例的功效。其中AuNP用检测抗体/寡核苷酸进行功能化，表现出84.3%的灵敏度和95.1%的特异性。该测定将改进用于腹部TB诊断的正在进行的算法。
