METHODS: A 40 year-old male patient presented to our clinic to evaluate an asymptomatic, slow-growing nodule localized on his left thigh. A CT scan revealed a well-defined, enhanced lesion with microcalcification. \"En bloc\" surgical resection of the lesion was performed and histopathology confirmed the diagnosis of pilomatrix carcinoma.
UNASSIGNED: Given its rarity, there are no definitive guidelines regarding PC treatment. However, surgical intervention with clear margins including wide local excision or Mohs micrographic surgery has been highly considered. In our case, wide excision of the lesion with clear margins was performed with no evidence of recurrence one year later.
CONCLUSIONS: Given the local aggressive nature of PC, appropriate surgical intervention is essential in decreasing the risk of recurrence. Wide excision with clear margins has been proposed to decrease the risk of recurrence. Additionally, total-body skin examination should be done 2-3 times annually to evaluate for recurrence or metastasis.
方法:一名40岁的男性患者到我们的诊所评估无症状,生长缓慢的结节位于他的左大腿上。CT扫描显示明确的,微钙化增强病变。对病灶进行了“En整块”手术切除,组织病理学证实诊断为毛囊癌。
■鉴于其稀有性,目前尚无关于PC治疗的明确指南.然而,包括广泛的局部切除或Mohs显微手术在内的手术干预被高度考虑。在我们的案例中,病灶广泛切除,边缘清晰,1年后无复发迹象.
结论:鉴于PC的局部侵袭性,适当的手术干预对于降低复发风险至关重要.已经提出了具有清晰边缘的广泛切除以降低复发风险。此外,应每年进行2-3次全身皮肤检查,以评估复发或转移。