Abstract：
Cytomorphological features of NUT carcinoma include sheets or discrete nests of primitive, monotonous, round to oval shaped tumour cells with high N/C ratio and brisk mitotic figures. Abrupt squamous differentiation might be a diagnostic hint. More than 50% positivity of NUT immunohistochemistry staining is diagnostic. NUT carcinoma represents a poorly differentiated malignancy by extremely aggressive clinical course and poor prognosis. It frequently manifests in midline organs, notably in the mediastinum and lung. The rising preferences for utilizing the EBUS-FNA procedure in diagnosing thoracic and lung lesions stems from its high diagnostic yield. Hence, recognizing the cytomorphological features of NUT carcinoma is crucial for timely treatment and improved patient survival.
摘要：
NUT癌的细胞形态学特征包括原始的片状或离散巢，单调,具有高N/C比和轻快的有丝分裂图的圆形至椭圆形肿瘤细胞。鳞状细胞分化突现可能是一个诊断提示。超过50%的NUT免疫组织化学染色阳性是诊断。NUT癌通过极其积极的临床过程和不良的预后来代表低分化的恶性肿瘤。它经常表现在中线器官，尤其是在纵隔和肺。利用EBUS-FNA程序诊断胸部和肺部病变的偏好上升源于其高诊断率。因此，认识到NUT癌的细胞形态学特征对于及时治疗和提高患者生存率至关重要。
