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Abstract：
Background The Quick Sequential Organ Failure Assessment (qSOFA) is a simple method for identifying patients with bacteremia; however, it is not accurate for predicting it. Performance status assessment involves the evaluation of daily activities and could be beneficial in predicting bacteremia. We aimed to evaluate whether adding Eastern Cooperative Oncology Group-Performance Status (ECOG-PS) to qSOFA could improve the prediction of bacteremia diagnosis in older patients admitted with suspected infections. Methods Data were gathered from individuals aged ≥65 years who were hospitalized with suspected bacteremia from 2018 to 2019. Two prediction models were contrasted employing logistic regression. The initial model exclusively incorporated the qSOFA score, while the second model integrated the Eastern Cooperative Oncology Group-Performance Status (ECOG-PS) alongside the qSOFA score. Results Among 1,114 enrolled patients, 221 (19.8%) had true bacteremia. The area under the curve of the qSOFA+ECOG-PS model did not show a statistically significant improvement in predictive capacity compared with that of the qSOFA model (0.544 vs. 0.554, p=0.162). Conclusions Adding the ECOG-PS score did not improve the performance of qSOFA for predicting bacteremia in older patients with suspected infection.
摘要：
背景：快速序贯器官功能衰竭评估（qSOFA）是一种用于识别菌血症患者的简单方法；然而，预测它是不准确的。绩效状态评估涉及对日常活动的评估，可能有助于预测菌血症。我们旨在评估在qSOFA中添加东部肿瘤协作组表现状态（ECOG-PS）是否可以改善对怀疑感染的老年患者菌血症诊断的预测。方法收集2018年至2019年年龄≥65岁的疑似菌血症住院患者的数据。采用逻辑回归对两种预测模型进行对比。初始模型仅包含qSOFA评分，而第二个模型整合了东部肿瘤协作组-绩效状态（ECOG-PS）和qSOFA评分。结果在1,114名患者中，221（19.8%）有真正的菌血症。与qSOFA模型相比，qSOFA+ECOG-PS模型的曲线下面积在预测能力上没有显示出统计学上的显着改善（0.544vs.0.554，p=0.162）。结论添加ECOG-PS评分并不能改善qSOFA预测老年疑似感染患者菌血症的性能。
