PDF(Pubmed)
Abstract：
Dimethacrylate-based chemistries feature extensively as resin monomers in dental resin-based materials due to their distinguished overall performance. However, challenges endure, encompassing inadequate mechanical attributes, volumetric shrinkage, and estrogenicity. Herein, we first synthesized a novel resin monomer, 9-armed starburst polyurethane acrylate (NPUA), via the grafting-onto approach. Compared to the primary commercial dental monomer 2,2-bis [p-(2\'-hydroxy-3\'-methacryloxypropoxy) phenyl] propane (Bis-GMA) (with a viscosity of 1,174 ± 3 Pa·s and volumetric shrinkage of 4.7% ± 0.1%), the NPUA monomer achieves the lower viscosity (158 ± 1 Pa·s), volumetric shrinkage (2.5% ± 0.1%), and cytotoxicity (P < 0.05). The NPUA-based resins exhibit the higher flexural strength, flexural modulus, hardness, and hydrophobicity and lower volumetric shrinkage, water absorption, and solubility compared to the Bis-GMA (70 wt%)/TEGDMA (30 wt%) resins. The NPUA-based composites exhibit significantly higher flexural strength, flexural modulus, and hardness and lower volumetric shrinkage (171.4 ± 3.0 MPa, 12.6 ± 0.5 GPa, 2.0 ± 0.2 GPa, and 3.4% ± 0.2%, respectively) compared to the Bis-GMA group (120.3 ± 4.7 MPa, 9.4 ± 0.7 GPa, 1.5 ± 0.1 GPa, and 4.7% ± 0.2%, respectively; P < 0.05). This work presents a viable avenue for augmenting the physicochemical attributes of dental resins.
摘要：
基于二甲基丙烯酸酯的化学物质由于其卓越的整体性能而广泛地作为牙科树脂基材料中的树脂单体。然而,挑战持续，包括不足的机械属性，体积收缩率，和雌激素。在这里，我们首先合成了一种新型的树脂单体,9臂星爆聚氨酯丙烯酸酯（NPUA），通过嫁接的方法。与主要商业牙科单体2,2-双[p-（2'-羟基-3'-甲基丙烯酰氧基丙氧基）苯基]丙烷（Bis-GMA）相比（粘度为1,174±3Pa·s，体积收缩率为4.7％±0.1％），NPUA单体达到较低的粘度(158±1Pa·s)，体积收缩率（2.5%±0.1%），和细胞毒性(P<0.05)。NPUA基树脂表现出较高的弯曲强度，弯曲模量,硬度,疏水性和较低的体积收缩率，吸水,和溶解度相比于Bis-GMA(70重量%)/TEGDMA(30重量%)树脂。基于NPUA的复合材料表现出明显更高的弯曲强度，弯曲模量,硬度和较低的体积收缩率(171.4±3.0MPa，12.6±0.5GPa，2.0±0.2GPa,和3.4%±0.2%，分别）与Bis-GMA组（120.3±4.7MPa，9.4±0.7GPa，1.5±0.1GPa，和4.7%±0.2%，分别；P<0.05）。这项工作为增强牙科树脂的物理化学属性提供了可行的途径。
