PDF(Pubmed)
Abstract：
UNASSIGNED: Hirsutism is a common endocrine disorder and its etiology varies from benign and idiopathic disorders to serious malignant diseases. Hirsutism creates negative impact on quality of life and considerable effects on fertility. Our objective was to determine the various causes of hirsutism in women presenting at two endocrine clinics.
UNASSIGNED: This cross-sectional study was conducted at Baqai Institute of Diabetology and Endocrinology, Karachi and at Jinnah hospital, Lahore from August 2020 to December 2021 women between 12-45 years of age with complains of hirsutism were included in the study. Severity of Hirsutism was evaluated using modified Ferriman-Gallwey score (FG). Patients with modified FG score of 8 or more were considered having hirsutism.
UNASSIGNED: The study had 113 patients with a mean age of 15.50+7.29 years with 89% having moderate hirsutism (FG score 16-25). Polycystic ovaries was the most common cause of hirsutism. Common sites for hirsutism included back (83%), arms (74%), buttocks (70%), and upper abdomen (47%). High BMI (p-value <0.01) and high Dehydroepiandrosterone levels were positively associated with the severity of hirsutism (p-value of 0.006.).
UNASSIGNED: The various causes of hirsutism identified were polycystic ovaries, followed by idiopathic, thyroid dysfunction, congenital adrenal hyperplasia, and hyperprolactinemia; therefore, all women presenting with hirsutism should be evaluated for potential serious and curable etiologies, before embarking on a treatment plan.
UNASSIGNED: This cross-sectional study was conducted at Baqai Institute of Diabetology and Endocrinology, Karachi and at Jinnah hospital, Lahore from August 2020 to December 2021 women between 12-45 years of age with complains of hirsutism were included in the study. Severity of Hirsutism was evaluated using modified Ferriman-Gallwey score (FG). Patients with modified FG score of 8 or more were considered having hirsutism.
UNASSIGNED: The study had 113 patients with a mean age of 15.50+7.29 years with 89% having moderate hirsutism (FG score 16-25). Polycystic ovaries was the most common cause of hirsutism. Common sites for hirsutism included back (83%), arms (74%), buttocks (70%), and upper abdomen (47%). High BMI (p-value <0.01) and high Dehydroepiandrosterone levels were positively associated with the severity of hirsutism (p-value of 0.006.).
UNASSIGNED: The various causes of hirsutism identified were polycystic ovaries, followed by idiopathic, thyroid dysfunction, congenital adrenal hyperplasia, and hyperprolactinemia; therefore, all women presenting with hirsutism should be evaluated for potential serious and curable etiologies, before embarking on a treatment plan.
摘要：
■多毛症是一种常见的内分泌疾病，其病因从良性和特发性疾病到严重的恶性疾病各不相同。多毛症会对生活质量产生负面影响，并对生育能力产生相当大的影响。我们的目的是确定在两个内分泌诊所就诊的女性多毛症的各种原因。
■这项横断面研究是在Baqai糖尿病和内分泌学研究所进行的，卡拉奇和真纳医院，拉合尔从2020年8月到2021年12月，患有多毛症的12-45岁女性被纳入研究。使用改良的Ferriman-Gallwey评分（FG）评估多毛症的严重程度。改良FG评分为8分或更高的患者被认为患有多毛症。
■该研究有113名患者，平均年龄15.50+7.29岁，其中89%患有中度多毛症（FG评分16-25）。多囊卵巢是多毛症的最常见原因。多毛症的常见部位包括背部(83%)，武器(74%)，臀部（70%），和上腹部（47%）。高BMI（p值<0.01）和高脱氢表雄酮水平与多毛症的严重程度呈正相关（p值为0.006。).
■确定的多毛症的各种原因是多囊卵巢，其次是特发性，甲状腺功能异常,先天性肾上腺增生,和高催乳素血症；因此，所有患有多毛症的女性都应接受潜在的严重和可治愈的病因评估，在开始治疗计划之前。
■这项横断面研究是在Baqai糖尿病和内分泌学研究所进行的，卡拉奇和真纳医院，拉合尔从2020年8月到2021年12月，患有多毛症的12-45岁女性被纳入研究。使用改良的Ferriman-Gallwey评分（FG）评估多毛症的严重程度。改良FG评分为8分或更高的患者被认为患有多毛症。
■该研究有113名患者，平均年龄15.50+7.29岁，其中89%患有中度多毛症（FG评分16-25）。多囊卵巢是多毛症的最常见原因。多毛症的常见部位包括背部(83%)，武器(74%)，臀部（70%），和上腹部（47%）。高BMI（p值<0.01）和高脱氢表雄酮水平与多毛症的严重程度呈正相关（p值为0.006。).
■确定的多毛症的各种原因是多囊卵巢，其次是特发性，甲状腺功能异常,先天性肾上腺增生,和高催乳素血症；因此，所有患有多毛症的女性都应接受潜在的严重和可治愈的病因评估，在开始治疗计划之前。
