PDF(Pubmed)
Abstract：
The droplet microfluidic device has become a widely used tool in fields such as physics, chemistry, and biology, but its complexity has limited its widespread application. This report introduces a modular and cost-effective droplet microfluidic device for the controlled production of complex emulsions, including oil and aqueous single emulsions, and double emulsions with varying numbers of encapsulated droplets. The droplet sizes can be precisely controlled by easily replacing flat needles and adjusting the needle position within an axially accelerated co-flow field. This modular device not only allows for easy repair and maintenance in case of device clogging or damage but can also be readily expanded to produce complex emulsions. The low-cost and user-friendly nature of the device greatly facilitates the widespread adoption and utilization of droplet microfluidics.
摘要：
微滴微流控装置已成为物理等领域广泛使用的工具,化学,和生物学,但是它的复杂性限制了它的广泛应用。本报告介绍了一种模块化且具有成本效益的液滴微流体装置，用于控制复杂乳液的生产，包括油和水性单一乳液，和具有不同数量的包封液滴的双重乳液。通过容易地更换扁平针和在轴向加速的同向流动场内调节针位置,可以精确地控制液滴尺寸。该模块化装置不仅允许在装置堵塞或损坏的情况下容易修理和维护,而且还可以容易地扩展以产生复杂的乳液。该装置的低成本和用户友好的性质极大地促进了液滴微流体的广泛采用和利用。
