PDF(Pubmed)
Abstract：
Despite the known beneficial effects of creatine in treating exercise-induced muscle damage (EIMD), its effectiveness remains unclear. This study investigates the recovery effect of creatine monohydrate (CrM) on EIMD. Twenty healthy men (21-36 years) were subjected to stratified, randomized, double-blind assignments. The creatine (CRE) and placebo (PLA) groups ingested creatine and crystalline cellulose, respectively, for 28 days. They subsequently performed dumbbell exercises while emphasizing eccentric contraction of the elbow flexors. The EIMD was evaluated before and after exercise. The range of motion was significantly higher in the CRE group than in the PLA group 24 h (h) post exercise. A similar difference was detected in maximum voluntary contraction at 0, 48, 96, and 168 h post exercise (p = 0.017-0.047). The upper arm circumference was significantly lower in the CRE group than in the PLA group at 48, 72, 96, and 168 h post exercise (p = 0.002-0.030). Similar variation was observed in the shear modulus of the biceps brachii muscle at 96 and 168 h post exercise (p = 0.003-0.021) and in muscle fatigue at 0 and 168 h post exercise (p = 0.012-0.032). These findings demonstrate CrM-mediated accelerated recovery from EIMD, suggesting that CrM is an effective supplement for EIMD recovery.
摘要：
尽管已知肌酸在治疗运动性肌肉损伤（EIMD）方面的有益作用，其有效性尚不清楚。本研究调查了肌酸一水合物（CrM）对EIMD的恢复作用。20名健康男性(21-36岁)接受了分层，随机化，双盲作业。肌酸（CRE）和安慰剂（PLA）组摄入肌酸和结晶纤维素，分别,28天随后，他们进行了哑铃练习，同时强调了肘屈肌的偏心收缩。在运动前后评估EIMD。运动后24h（h），CRE组的运动范围明显高于PLA组。在运动后0、48、96和168小时的最大自愿收缩中检测到类似的差异（p=0.017-0.047）。运动后48、72、96和168h，CRE组的上臂周长明显低于PLA组（p=0.002-0.030）。在运动后96和168小时的肱二头肌剪切模量（p=0.003-0.021）以及运动后0和168小时的肌肉疲劳（p=0.012-0.032）中观察到类似的变化。这些发现表明CrM介导的EIMD加速恢复，表明CrM是EIMD恢复的有效补充。
