PDF(Pubmed)
Abstract：
T. gondii is the causal agent of toxoplasmosis, a worldwide zoonotic disease relevant in human and veterinary medicine. In Algeria, few reports focused on the presence and circulation of this parasite in the local goat population. The aim of the survey was to evaluate toxoplasmosis seroprevalence and associated risk factors. Sera from 460 goats reared on 72 farms in northeastern Algeria were collected and tested for IgG antibodies to T. gondii by an indirect ELISA. To identify risk factors, a linear regression analysis of the variables was performed. Anti-T. gondii antibodies were found in 94.44% (68/72; 95% CI: 73.34-119.73) of goat farms and in 53.26% (245/460; 95% CI: 46.80-60.36) at the individual level. The multivariable analysis showed that seasonal pasture (OR = 3.804; 95% CI: 3.321-4.358; p = 0.003), presence of water source in pasture area (OR = 4.844; 95% CI: 1.942-7.789; p = 0.0004), use of anthelminthics (OR = 2.640; 95% CI: 1.592-3.146; p = 0.036), number of cats, hygiene, proportion of abortions, number of abortions in the last year, year of sampling, region, and season were the variables significantly associated with T. gondii seropositivity. Abortions in goat herds seem to be related to T. gondii exposure, thus it is crucial to undertake measures and strategies to reduce, control, and prevent toxoplasmosis infection in goats, and thereby in humans, from Algeria.
摘要：
弓形虫是弓形虫病的病因，一种与人类和兽医学相关的世界性人畜共患疾病。在阿尔及利亚,很少有报道集中在当地山羊种群中这种寄生虫的存在和循环。调查的目的是评估弓形虫病的血清阳性率和相关的危险因素。收集了阿尔及利亚东北部72个农场饲养的460只山羊的血清，并通过间接ELISA测试了弓形虫的IgG抗体。为了识别风险因素，对变量进行线性回归分析.反T.在个体水平上，在94.44％（68/72；95％CI：73.34-119.73）的山羊养殖场和53.26％（245/460；95％CI：46.80-60.36）中发现了刚地抗体。多变量分析显示,季节性牧场(OR=3.804;95%CI:3.321-4.358;p=0.003),牧区存在水源(OR=4.844；95%CI：1.942-7.789；p=0.0004)，使用驱虫药（OR=2.640；95％CI：1.592-3.146；p=0.036），猫的数量,卫生,堕胎比例，去年堕胎的数量，采样年份，区域,和季节是与弓形虫血清阳性显着相关的变量。羊群的流产似乎与弓形虫暴露有关，因此，采取措施和战略减少，control,预防山羊弓形虫病感染，因此在人类中，来自阿尔及利亚。
