IKZF1 中的非编码调节变体会增加西班牙裔 / 拉丁裔儿童的急性淋巴细胞白血病风险。
关键词: B-ALL GWAS IKZF1 Indigenous American acute lymphoblastic leukemia cancer disparity cancer predisposition childhood leukemia fine-mapping hematopoiesis
Mesh : Humans Child Genetic Predisposition to Disease / genetics Polymorphism, Single Nucleotide Transcription Factors / genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics Hispanic or Latino / genetics Ikaros Transcription Factor / genetics
来 源:
DOI:10.1016/j.xgen.2024.100526
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