PDF(Pubmed)
Abstract：
The incidence of paracoccidioidomycosis (PCM) varies in Latin America, and it is influenced by environmental factors. This study evaluated the distribution of PCM acute/subacute form (AF) cases and their correlation with geoclimatic factors in the Mato Grosso do Sul (MS) state. The study included 81 patients diagnosed with the PCM/AF at the University Hospital of the Federal University of Mato Grosso do Sul between January 1980 and February 2022. Geographic coordinates, health microregion of patient\'s residence, compensated average temperature, relative air humidity (RH), El Niño Southern Oscillation (ENSO), and average global temperature were analyzed. The highest incidence was observed in the Aquidauana (7/100,000 inhabitants), while Campo Grande, the state\'s capital, had the highest number (n = 34; 42.4%) and density (4.4 cases/km2) of cases. The number of cases increased during extended periods of the El Niño phenomenon. A positive correlation was found between higher RH and PCM/AF cases. Most PCM/AF cases were found in areas with loamy soils and RH ranging from 60.8 to 73.6%. In MS, the health microregions of PCM/AF patients are characterized by deforestation for agricultural and pasture use, coupled with loamy soils and specific climatic phenomena leading to higher soil humidity.
摘要：
拉丁美洲的副球菌病（PCM）的发病率各不相同，它受到环境因素的影响。这项研究评估了南马托格罗索（MS）状态下PCM急性/亚急性形式（AF）病例的分布及其与地气候因素的相关性。该研究包括1980年1月至2022年2月在南马托格罗索联邦大学大学医院诊断为PCM/AF的81例患者。地理坐标,患者居住地的健康微区域，补偿平均温度，相对空气湿度（RH），厄尔尼诺南方涛动(ENSO)并对全球平均气温进行了分析。在Aquidauana（7/100,000居民）中发病率最高，而CampoGrande,该州的首都，病例数（n=34；42.4％）和密度（4.4例/km2）最高。在厄尔尼诺现象的长期期间，病例数量有所增加。发现较高的RH与PCM/AF病例之间呈正相关。大多数PCM/AF病例是在肥沃的土壤和RH范围为60.8至73.6％的地区发现的。在MS中，PCM/AF患者的健康微区域的特征是用于农业和牧场的森林砍伐，再加上肥沃的土壤和特定的气候现象，导致土壤湿度较高。
