PDF(Pubmed)
Abstract：
BACKGROUND: In geriatrics, explicit criteria for potentially inappropriate prescriptions (PIPs) are useful for optimizing drug use.
OBJECTIVE: To produce an expert consensus on explicit definitions of antibiotic-PIPs for hospitalized older patients.
METHODS: We conducted a Delphi survey involving French experts on antibiotic stewardship in hospital settings. During the survey\'s rounds, the experts gave their opinion on each explicit definition, and could suggest new definitions. Definitions with a 1-to-9 Likert score of between 7 and 9 from at least 75% of the participants were adopted. The results were discussed during consensus meetings after each round.
RESULTS: Of the 155 invited experts, 128 (82.6%) participated in the whole survey: 59 (46%) infectious diseases specialists, 45 (35%) geriatricians, and 24 (19%) other specialists. In Round 1, 65 explicit definitions were adopted and 21 new definitions were suggested. In Round 2, 35 other explicit definitions were adopted. The results were validated during consensus meetings (with 44 participants after Round 1, and 54 after Round 2).
CONCLUSIONS: The present study is the first to have provided a list of explicit definitions of potentially inappropriate antibiotic prescriptions for hospitalized older patients. It might help to disseminate key messages to prescribers and reduce inappropriate prescriptions of antibiotics.
OBJECTIVE: To produce an expert consensus on explicit definitions of antibiotic-PIPs for hospitalized older patients.
METHODS: We conducted a Delphi survey involving French experts on antibiotic stewardship in hospital settings. During the survey\'s rounds, the experts gave their opinion on each explicit definition, and could suggest new definitions. Definitions with a 1-to-9 Likert score of between 7 and 9 from at least 75% of the participants were adopted. The results were discussed during consensus meetings after each round.
RESULTS: Of the 155 invited experts, 128 (82.6%) participated in the whole survey: 59 (46%) infectious diseases specialists, 45 (35%) geriatricians, and 24 (19%) other specialists. In Round 1, 65 explicit definitions were adopted and 21 new definitions were suggested. In Round 2, 35 other explicit definitions were adopted. The results were validated during consensus meetings (with 44 participants after Round 1, and 54 after Round 2).
CONCLUSIONS: The present study is the first to have provided a list of explicit definitions of potentially inappropriate antibiotic prescriptions for hospitalized older patients. It might help to disseminate key messages to prescribers and reduce inappropriate prescriptions of antibiotics.
摘要：
背景：在老年医学中，潜在不适当处方(PIPs)的明确标准可用于优化药物使用.
目的：就住院老年患者抗生素-PIPs的明确定义达成专家共识。
方法：我们进行了一项Delphi调查，调查涉及医院环境中抗生素管理的法国专家。在调查的回合中，专家们对每个明确的定义发表了意见，并可以提出新的定义。采用了至少75％的参与者的1-9Likert评分在7至9之间的定义。在每一轮会议之后的共识会议上讨论了结果。
结果：在155位受邀专家中，128名(82.6%)参与了整个调查:59名(46%)传染病专家，45名(35%)老年医生，和24名（19%）其他专家。在第一轮中，通过了65个明确的定义，并提出了21个新定义。在第二轮中，通过了35个其他明确的定义。结果在共识会议上得到验证（第一轮后有44名参与者，第二轮后有54名参与者）。
结论：本研究首次提供了对住院老年患者可能不适当的抗生素处方的明确定义。它可能有助于向处方者传播关键信息，并减少不适当的抗生素处方。
目的：就住院老年患者抗生素-PIPs的明确定义达成专家共识。
方法：我们进行了一项Delphi调查，调查涉及医院环境中抗生素管理的法国专家。在调查的回合中，专家们对每个明确的定义发表了意见，并可以提出新的定义。采用了至少75％的参与者的1-9Likert评分在7至9之间的定义。在每一轮会议之后的共识会议上讨论了结果。
结果：在155位受邀专家中，128名(82.6%)参与了整个调查:59名(46%)传染病专家，45名(35%)老年医生，和24名（19%）其他专家。在第一轮中，通过了65个明确的定义，并提出了21个新定义。在第二轮中，通过了35个其他明确的定义。结果在共识会议上得到验证（第一轮后有44名参与者，第二轮后有54名参与者）。
结论：本研究首次提供了对住院老年患者可能不适当的抗生素处方的明确定义。它可能有助于向处方者传播关键信息，并减少不适当的抗生素处方。
