METHODS: A 3-month outpatient intervention consisting of a diet and exercise program was provided to 153 participants. Psychological distress, appetite, and behavior were assessed at the beginning and end of the study. Anthropometric measurements were taken at baseline and six months.
RESULTS: After the structural equation model was developed, it was discovered that the psychological status of people with obesity and weight cycling histories correlated with the weight loss outcome effect (three and six months). This effect was mediated by factors related to eating behavior. Associative psychological factors had a direct effect on eating behavior (three months: β = 0.181, 95% CI: 0.055-0.310; six months: β = 0.182, 95% CI: 0.039-0.332) and appetite had a direct effect on eating behavior (three months: β = 0.600, 95% CI: 0.514-0.717; six months: β = 0.581, 95% CI: 0.457-0.713), both of which were significant (p < 0.01). At three months, psychological distress has a more substantial positive impact on weight change, with eating behavior acting as a partial mediator. At six months, there was no support for appetite\'s moderating role in eating behavior.
CONCLUSIONS: The findings suggest that psychological interventions should be strengthened to improve weight loss effectiveness, particularly in participants with a history of weight cycling, making weight loss more complicated and prone to rebound.
BACKGROUND: The study has been registered in Clinical Trials (NCT05311462).
方法:对153名参与者进行了为期3个月的门诊干预,包括饮食和运动计划。心理困扰,食欲,和行为在研究开始和结束时进行评估。在基线和6个月时进行人体测量。
结果:结构方程模型建立后,研究发现,肥胖和体重循环史患者的心理状况与减肥效果(3个月和6个月)相关。这种效应是由与饮食行为相关的因素介导的。联想心理因素对进食行为有直接影响(三个月:β=0.181,95%CI:0.055-0.310;六个月:β=0.182,95%CI:0.039-0.332),食欲对进食行为有直接影响(三个月:β=0.600,95%CI:0.514-0.717;六个月:β=0.581,95%CI:0.457-0.713),两者均显著(p<0.01)。三个月后,心理困扰对体重变化有更大的积极影响,饮食行为充当部分中介。六个月的时候,没有支持食欲在饮食行为中的调节作用。
结论:研究结果表明,应加强心理干预以提高减肥效果,特别是有体重自行车史的参与者,使减肥更加复杂,容易反弹。
背景:该研究已在临床试验中注册(NCT05311462)。