PDF(Pubmed)
Abstract：
BACKGROUND: Skin diseases such as impetigo pose a significant public health challenge in low resource settings. Despite this, there is a dearth of epidemiological data on the prevalence of this condition in Ghana.
METHODS: We conducted a cross sectional study in three settings in Ghana: community members in East Mamprusi district in the North East region, a secondary school in Sekyere East district, and inmates of the Kumasi central prisons both in the Ashanti region. Following a period of training, we performed a standardised skin examination on each participant to assess for scabies and impetigo. We calculated the prevalence of each skin condition and investigated determinants of impetigo.
UNASSIGNED: Of the 1327 participants [males 64.1% and median age 22 (16-29) years], 746 (56.2%) had scabies and 186 (14%) had impetigo which was usually very mild or mild in severity. Most participants with impetigo also had scabies (161/186, 86.6%). Having an itch [RR 6.05 (95% CI 2.53-14.47)], presence of scabies burrows [RR 1.99 (95% CI 1.54-2.59)], clinical scabies [RR 3.15 (2.11-4.72)] or being in preschool [RR 4.56 (1.78-11.67)] increased the risk for impetigo. A combination of the presence of clinical scabies, age, sex and itch most accurately predicted the odds of having impetigo.
CONCLUSIONS: There is substantial burden of impetigo and scabies in Ghana. There is a need to institute measures to improve detection and control of these common dermatoses as part of Universal Health Coverage package to reduce the scourge of the diseases in this setting.
METHODS: We conducted a cross sectional study in three settings in Ghana: community members in East Mamprusi district in the North East region, a secondary school in Sekyere East district, and inmates of the Kumasi central prisons both in the Ashanti region. Following a period of training, we performed a standardised skin examination on each participant to assess for scabies and impetigo. We calculated the prevalence of each skin condition and investigated determinants of impetigo.
UNASSIGNED: Of the 1327 participants [males 64.1% and median age 22 (16-29) years], 746 (56.2%) had scabies and 186 (14%) had impetigo which was usually very mild or mild in severity. Most participants with impetigo also had scabies (161/186, 86.6%). Having an itch [RR 6.05 (95% CI 2.53-14.47)], presence of scabies burrows [RR 1.99 (95% CI 1.54-2.59)], clinical scabies [RR 3.15 (2.11-4.72)] or being in preschool [RR 4.56 (1.78-11.67)] increased the risk for impetigo. A combination of the presence of clinical scabies, age, sex and itch most accurately predicted the odds of having impetigo.
CONCLUSIONS: There is substantial burden of impetigo and scabies in Ghana. There is a need to institute measures to improve detection and control of these common dermatoses as part of Universal Health Coverage package to reduce the scourge of the diseases in this setting.
摘要：
背景：脓疱疮等皮肤病在资源匮乏的环境中构成了重大的公共卫生挑战。尽管如此,加纳缺乏这种情况的流行病学数据。
方法：我们在加纳的三个环境中进行了横断面研究：东北地区东Mamprusi区的社区成员，Sekyere东区的一所中学,和阿散蒂地区库马西中央监狱的囚犯。经过一段时间的训练,我们对每位参与者进行了标准化的皮肤检查,以评估是否有sc疮和脓疱疮.我们计算了每种皮肤状况的患病率，并研究了脓疱病的决定因素。
■在1327名参与者中[男性64.1%，年龄中位数为22岁（16-29岁）]，746例（56.2％）患有sc疮，186例（14％）患有脓疱病，通常严重程度非常轻或轻度。大多数脓疱疮患者也有疮（161/186，86.6％）。瘙痒[RR6.05（95%CI2.53-14.47）]，[RR1.99（95%CI1.54-2.59）]，临床[RR3.15(2.11-4.72)]或学龄前[RR4.56(1.78-11.67)]会增加脓疱病的风险.结合了临床上的脓肿，年龄,性和瘙痒最准确地预测了患脓疱病的几率。
结论：加纳的脓疱疮和sc疮负担很大。作为全民健康覆盖一揽子计划的一部分，有必要采取措施改善对这些常见皮肤病的检测和控制，以减少这种情况下的疾病祸害。
方法：我们在加纳的三个环境中进行了横断面研究：东北地区东Mamprusi区的社区成员，Sekyere东区的一所中学,和阿散蒂地区库马西中央监狱的囚犯。经过一段时间的训练,我们对每位参与者进行了标准化的皮肤检查,以评估是否有sc疮和脓疱疮.我们计算了每种皮肤状况的患病率，并研究了脓疱病的决定因素。
■在1327名参与者中[男性64.1%，年龄中位数为22岁（16-29岁）]，746例（56.2％）患有sc疮，186例（14％）患有脓疱病，通常严重程度非常轻或轻度。大多数脓疱疮患者也有疮（161/186，86.6％）。瘙痒[RR6.05（95%CI2.53-14.47）]，[RR1.99（95%CI1.54-2.59）]，临床[RR3.15(2.11-4.72)]或学龄前[RR4.56(1.78-11.67)]会增加脓疱病的风险.结合了临床上的脓肿，年龄,性和瘙痒最准确地预测了患脓疱病的几率。
结论：加纳的脓疱疮和sc疮负担很大。作为全民健康覆盖一揽子计划的一部分，有必要采取措施改善对这些常见皮肤病的检测和控制，以减少这种情况下的疾病祸害。
