Abstract：
BACKGROUND: It is not yet clear if gravidity and parity have any relationships with the electrodiagnostic parameters of carpal tunnel syndrome (CTS).
OBJECTIVE: To determine whether there is a relationship between electrodiagnostic findings, gravidity, and parity number in CTS.
METHODS: Female patients over 18 years of age with CTS were included in this retrospective cohort study. The gravidity/parity number, median nerve compound muscle action potential (CMAP), and compound nerve action potential (CNAP) of the patients were analyzed. The two subgroups of the Boston carpal tunnel syndrome questionnaire (BCTSQ): The Symptom Severity Scale (SSS) and Functional Severity Scale (FSS) were applied to the patients. CTS patients were divided into two groups aged at first pregnancy ≤20 years and >20 years.
RESULTS: One hundred and eight CTS extremities (seven right-sided CTS, three left-sided CTS, 49 bilateral CTS) of 59 patients were included. The median (interquartile range: 25%-75%) number of gravidity, parity, and abortion were 3 (2-5), 3 (2-4), and 0 (0-0), respectively. Right-sided CTS patients at the age of first pregnancy ≤20 years had higher BCTSQ-SSS/FSS scores and median nerve CMAP latency compared to patients at the age of first pregnancy >20 years (P = 0.029 for SSS; P = 0.042 for FSS; and P = 0.041 for CMAP latency). A negative correlation was found between the gravidity/parity numbers and median nerve CNAP/CMAP amplitudes (P = 0.028/0.031, r = -0.293/-0.289 for CNAP amplitude; and P = 0.006/0.035, r = -0.363/-0.283 for CMAP amplitude).
CONCLUSIONS: Neurophysiological findings worsen as the number of gravidity and parity increase. Electrodiagnostic and clinical features of CTS may be worsening in females below 20 years at first pregnancy.
OBJECTIVE: To determine whether there is a relationship between electrodiagnostic findings, gravidity, and parity number in CTS.
METHODS: Female patients over 18 years of age with CTS were included in this retrospective cohort study. The gravidity/parity number, median nerve compound muscle action potential (CMAP), and compound nerve action potential (CNAP) of the patients were analyzed. The two subgroups of the Boston carpal tunnel syndrome questionnaire (BCTSQ): The Symptom Severity Scale (SSS) and Functional Severity Scale (FSS) were applied to the patients. CTS patients were divided into two groups aged at first pregnancy ≤20 years and >20 years.
RESULTS: One hundred and eight CTS extremities (seven right-sided CTS, three left-sided CTS, 49 bilateral CTS) of 59 patients were included. The median (interquartile range: 25%-75%) number of gravidity, parity, and abortion were 3 (2-5), 3 (2-4), and 0 (0-0), respectively. Right-sided CTS patients at the age of first pregnancy ≤20 years had higher BCTSQ-SSS/FSS scores and median nerve CMAP latency compared to patients at the age of first pregnancy >20 years (P = 0.029 for SSS; P = 0.042 for FSS; and P = 0.041 for CMAP latency). A negative correlation was found between the gravidity/parity numbers and median nerve CNAP/CMAP amplitudes (P = 0.028/0.031, r = -0.293/-0.289 for CNAP amplitude; and P = 0.006/0.035, r = -0.363/-0.283 for CMAP amplitude).
CONCLUSIONS: Neurophysiological findings worsen as the number of gravidity and parity increase. Electrodiagnostic and clinical features of CTS may be worsening in females below 20 years at first pregnancy.
摘要：
背景：尚不清楚妊娠和奇偶校验是否与腕管综合征（CTS）的电诊断参数有任何关系。
目的：为了确定电诊断结果之间是否存在关系，妊娠,和CTS中的奇偶校验号。
方法：这项回顾性队列研究包括年龄超过18岁的女性CTS患者。妊娠/奇偶校验数，正中神经复合肌肉动作电位（CMAP），并对患者的复合神经动作电位(CNAP)进行分析。波士顿腕管综合征问卷（BCTSQ）的两个亚组：对患者应用症状严重程度量表（SSS）和功能严重程度量表（FSS）。将CTS患者分为两组，年龄在首次妊娠≤20岁和>20岁。
结果：一百零八个CTS末端（七个右侧CTS，三个左侧CTS，包括59例患者的49例双侧CTS）。妊娠的中位数（四分位数范围：25％-75％），奇偶校验，流产为3（2-5），3（2-4）和0（0-0），分别。与首次妊娠年龄>20岁的患者相比，首次妊娠年龄≤20岁的右侧CTS患者的BCTSQ-SSS/FSS评分和正中神经CMAP潜伏期更高（SSSP=0.029；FSSP=0.042；CMAP潜伏期P=0.041）。妊娠/奇偶数与正中神经CNAP/CMAP振幅呈负相关（CNAP振幅P=0.028/0.031，r=-0.293/-0.289；CMAP振幅P=0.006/0.035，r=-0.363/-0.283）。
结论：随着妊娠次数和产次次数的增加，神经生理学发现恶化。首次怀孕20岁以下的女性，CTS的电诊断和临床特征可能会恶化。
目的：为了确定电诊断结果之间是否存在关系，妊娠,和CTS中的奇偶校验号。
方法：这项回顾性队列研究包括年龄超过18岁的女性CTS患者。妊娠/奇偶校验数，正中神经复合肌肉动作电位（CMAP），并对患者的复合神经动作电位(CNAP)进行分析。波士顿腕管综合征问卷（BCTSQ）的两个亚组：对患者应用症状严重程度量表（SSS）和功能严重程度量表（FSS）。将CTS患者分为两组，年龄在首次妊娠≤20岁和>20岁。
结果：一百零八个CTS末端（七个右侧CTS，三个左侧CTS，包括59例患者的49例双侧CTS）。妊娠的中位数（四分位数范围：25％-75％），奇偶校验，流产为3（2-5），3（2-4）和0（0-0），分别。与首次妊娠年龄>20岁的患者相比，首次妊娠年龄≤20岁的右侧CTS患者的BCTSQ-SSS/FSS评分和正中神经CMAP潜伏期更高（SSSP=0.029；FSSP=0.042；CMAP潜伏期P=0.041）。妊娠/奇偶数与正中神经CNAP/CMAP振幅呈负相关（CNAP振幅P=0.028/0.031，r=-0.293/-0.289；CMAP振幅P=0.006/0.035，r=-0.363/-0.283）。
结论：随着妊娠次数和产次次数的增加，神经生理学发现恶化。首次怀孕20岁以下的女性，CTS的电诊断和临床特征可能会恶化。
