关键词: Blood pressure Cranial involvement Eclampsia Posterior reversible encephalopathy syndrome Seizure recurrence

Mesh : Humans Female Posterior Leukoencephalopathy Syndrome / diagnostic imaging physiopathology etiology complications Pregnancy Eclampsia / physiopathology Adult Recurrence Seizures / etiology physiopathology Magnetic Resonance Imaging Blood Pressure / physiology Young Adult Risk Factors

来  源:   DOI:10.1159/000538519

Abstract:
OBJECTIVE: Posterior reversible encephalopathy syndrome (PRES) is a clinic radiological disorder characterized by headache, epileptic seizure, encephalopathy, visual impairment, and focal neurological deficits. Gestational hypertension, which is a significant risk factor for PRES, may cause significant morbidity and mortality among pregnant women.
METHODS: Twenty-four patients with PRES caused by eclampsia who were admitted to our hospital in the last 5 years were included in this study.
METHODS: Blood pressure at admission, the number of regions with vasogenic edema in the brain, and recurrent seizures were noted. Patients were divided into three groups: mild, moderate, and severe.
RESULTS: Using Kruskal-Wallis and Pearson χ2 tests, there was no statistical significance between the groups in terms of cranial involvement (p = 0.471). However, binary logistic regression analysis showed that seizure recurrence increased in correlation with blood pressure (p = 0.04).
CONCLUSIONS: PRES is a rare syndrome associated with several etiologies. In our study, only patients with PRES due to eclampsia were included. Therefore, the number of included patients was limited (24 participants).
CONCLUSIONS: PRES may occur in eclamptic patients with mild, moderate, or severe blood pressure values. Evaluation by magnetic resonance imaging is needed to confirm the diagnosis. Early and rapid treatment is essential for reducing morbidity and mortality among pregnant women.
摘要:
目的:可逆性后部脑病综合征(PRES)是一种以头痛为特征的临床放射学疾病,癫痫发作,脑病,视力障碍,和局灶性神经功能缺损.妊娠期高血压,这是PRES的重要风险因素,可能导致孕妇的大量发病率和死亡率。
方法:本研究纳入了我院近5年收治的24例子痫引起的PRES患者。
方法:入院时的血压,大脑中血管源性水肿的区域数量,并注意到反复发作。患者分为三组:轻度,中度,和严重。
结果:使用Kruskal-Wallis和Pearson卡方检验,两组间颅内受累情况无统计学意义(P:0.471)。然而,二元logistic回归分析显示,癫痫发作复发与血压相关(P:0.04)。在我们的研究中,仅包括因子痫引起的PRES患者。因此,纳入的患者数量有限(24名参与者).
结论:PRES可能发生在轻度子痫患者中,中度或重度血压值。需要通过MRI进行评估以确认诊断。早期和快速治疗对于降低孕妇的发病率和死亡率至关重要。
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