METHODS: A clinical case study of a patient with sitosterolemia with slow healing surgical wound from coronary artery bypass surgery is described. Treatment of sitosterolemia is aimed at lowering plasma plant sterol levels with dietary restriction intake of both animal- and plant-based sterols. However, plant-based products (collagen, chitosan, etc) are also used for wound dressings, so alternative wound dressings were selected to decrease the possibility of systemic absorption.
CONCLUSIONS: This case study describes a young adult male with sitosterolemia who presented with a slow healing surgical incision following coronary artery bypass surgery. Sitosterolemia is often characterized by atherosclerosis of the coronary arteries that occurs in children and early adulthood, especially affecting men. Treatment is aimed at lowering plasma sterol levels with the restriction of animal and plant sterols. There is considerable interest today in natural versus synthetic wound care products. Dressings containing chitosan, cellulose, collagen, etc, to be avoided to decrease the chance of systemic absorption.
方法:描述了一例因冠状动脉搭桥手术导致的手术伤口愈合缓慢的谷甾醇血症患者的临床病例研究。谷甾醇血症的治疗旨在通过饮食限制摄入基于动物和植物的甾醇来降低血浆植物甾醇水平。然而,植物性产品(胶原蛋白,壳聚糖,等)也用于伤口敷料,因此选择替代伤口敷料以降低全身吸收的可能性。
结论:本病例研究描述了一名患有谷甾醇血症的年轻成年男性,在冠状动脉搭桥手术后出现手术切口缓慢愈合。谷甾醇血症通常以儿童和成年早期发生的冠状动脉粥样硬化为特征。尤其是影响男人。治疗的目的是在限制动物和植物甾醇的情况下降低血浆甾醇水平。目前对天然与合成的伤口护理产品有相当大的兴趣。含壳聚糖的敷料,纤维素,胶原蛋白,etc,要避免减少全身吸收的机会。