PDF(Pubmed)
Abstract：
Trichomonas gallinae is a parasite that causes canker and severe loss and death, especially in young pigeons. Metronidazole (MTZ) is the recommended drug for treating avian trichomoniasis. Due to drug resistance, non-chemical alternatives, such as medicinal plant extracts, are also considered possible therapies for this disease.
This study compares the antitrichomonal effects of MTZ with extracts of Camellia sinensis and Ziziphus vulgaris on T. gallinae in vitro.
Samples of T. gallinae were taken from infected pigeons. Multi-well plates with different concentrations (5, 10, 25, 50 and 100 µg/mL) of plant extracts were used for the in vitro study.
The minimum inhibitory concentration (MIC) of C. sinensis extract was 25 µg/mL over 24 h, compared to 50 µg/mL for MTZ. The MIC value of the Z. vulgaris extracts was 50 µg/mL.
The results suggest that the extracts of Z. vulgaris and C. sinensis, as potential natural agents, could have anti-avian trichomoniasis properties. This study also shows that MTZ, C. sinensis and Z. vulgaris are equally effective in preventing the growth of T. gallinae trophozoites in the culture.
This study compares the antitrichomonal effects of MTZ with extracts of Camellia sinensis and Ziziphus vulgaris on T. gallinae in vitro.
Samples of T. gallinae were taken from infected pigeons. Multi-well plates with different concentrations (5, 10, 25, 50 and 100 µg/mL) of plant extracts were used for the in vitro study.
The minimum inhibitory concentration (MIC) of C. sinensis extract was 25 µg/mL over 24 h, compared to 50 µg/mL for MTZ. The MIC value of the Z. vulgaris extracts was 50 µg/mL.
The results suggest that the extracts of Z. vulgaris and C. sinensis, as potential natural agents, could have anti-avian trichomoniasis properties. This study also shows that MTZ, C. sinensis and Z. vulgaris are equally effective in preventing the growth of T. gallinae trophozoites in the culture.
摘要：
背景：鸡毛滴虫是一种导致溃疡和严重损失和死亡的寄生虫，尤其是幼鸽。甲硝唑（MTZ）是治疗禽类滴虫病的推荐药物。由于耐药性,非化学替代品，如药用植物提取物，也被认为是这种疾病的可能疗法。
目的：本研究比较了MTZ与山茶和酸枣仁提取物对鸡毛虫的体外抗滴虫作用。
方法：从被感染的鸽子中采集鸡毛虫的样本。具有不同浓度（5、10、25、50和100µg/mL）的植物提取物的多孔板用于体外研究。
结果：在24小时内，中华绒螯蟹提取物的最低抑菌浓度（MIC）为25µg/mL，与MTZ的50µg/mL相比。Z.vulgaris提取物的MIC值为50μg/mL。
结论：结果表明，作为潜在的自然因子，可能有抗禽滴虫的特性.这项研究还表明，MTZ，C.sinensis和Z.vulgaris在防止培养物中的T.gallinae滋养体的生长方面同样有效。
目的：本研究比较了MTZ与山茶和酸枣仁提取物对鸡毛虫的体外抗滴虫作用。
方法：从被感染的鸽子中采集鸡毛虫的样本。具有不同浓度（5、10、25、50和100µg/mL）的植物提取物的多孔板用于体外研究。
结果：在24小时内，中华绒螯蟹提取物的最低抑菌浓度（MIC）为25µg/mL，与MTZ的50µg/mL相比。Z.vulgaris提取物的MIC值为50μg/mL。
结论：结果表明，作为潜在的自然因子，可能有抗禽滴虫的特性.这项研究还表明，MTZ，C.sinensis和Z.vulgaris在防止培养物中的T.gallinae滋养体的生长方面同样有效。
