PDF(Pubmed)
Abstract：
Coronavirus infection disease-19 (COVID-19) is a worldwide catastrophic emergency that first appeared in late 2019, in Wuhan, China. COVID-19 is a multitropism disease that first affects lung tissue. However, extrapulmonary manifestations have been suspected from the first COVID-19 cases. The ocular signs and symptoms were from the early changes that occur during the course of the disease. Changes in the anterior eye segment have a relatively higher incidence than the posterior eye segment. Of which, conjunctivitis, COVID-19 pharyngioceratoconjuctivitis, iridocyclitis, corneal punctate epitheliopathy, and pathomorphological changes in the physio-anatomy of the anterior eye segment. The potential pathogenesis includes direct penetration of the virus into the eye (conjunctiva, lumbus, and cornea) or due to a systemic pathway through viremia, as well as due to autoimmune antibodies against the ocular structure (immune privilege). The presence of ocular manifestations of the external anterior fibrous layer suggests a mild course of the disease.
摘要：
冠状病毒感染疾病-19(COVID-19)是一种全球性的灾难性紧急情况，首次出现在2019年底的武汉，中国。COVID-19是一种多向性疾病，首先影响肺组织。然而,第一例COVID-19病例怀疑肺外表现.眼部体征和症状来自疾病过程中发生的早期变化。前眼段的变化具有比后眼段相对更高的发生率。其中，结膜炎,COVID-19咽喉炎，虹膜睫状体炎,角膜点状上皮病，和眼前段生理解剖的病理形态学变化。潜在的发病机理包括病毒直接渗透到眼睛中（结膜，lumbus,和角膜）或由于病毒血症的全身途径，以及由于针对眼部结构的自身免疫抗体（免疫特权）。外部前纤维层的眼部表现的存在表明该疾病的轻度病程。
