PDF(Pubmed)
Abstract：
BACKGROUND: Cryptococcosis presenting as endobronchial obstruction and lung collapse is an extremely rare occurrence. While these patients were treated with antifungal agents, unfortunately, half of them showed a suboptimal response.
METHODS: A 45-year-old immunocompetent male was admitted to the hospital due to a cough, yellow phlegm, and dyspnea persisting for 5 months. Chest computer tomography revealed a mass in the right main bronchus accompanied by right lower lobe atelectasis.
METHODS: Endobronchial cryptococcosis presenting as endobronchial obstruction and lung collapse.
METHODS: Early rigid bronchoscopic therapy was performed to resect endobronchial obstruction, which combined with antifungal agent.
RESULTS: The patient recovered well with completely clinical and radiologic resolution at 1 year follow-up.
CONCLUSIONS: This case provides a good example of successful utilization of the early respiratory interventional therapy combined with antifungal agent in obstructive endobronchial cryptococcosis.
METHODS: A 45-year-old immunocompetent male was admitted to the hospital due to a cough, yellow phlegm, and dyspnea persisting for 5 months. Chest computer tomography revealed a mass in the right main bronchus accompanied by right lower lobe atelectasis.
METHODS: Endobronchial cryptococcosis presenting as endobronchial obstruction and lung collapse.
METHODS: Early rigid bronchoscopic therapy was performed to resect endobronchial obstruction, which combined with antifungal agent.
RESULTS: The patient recovered well with completely clinical and radiologic resolution at 1 year follow-up.
CONCLUSIONS: This case provides a good example of successful utilization of the early respiratory interventional therapy combined with antifungal agent in obstructive endobronchial cryptococcosis.
摘要：
背景：表现为支气管内阻塞和肺塌陷的隐球菌病极为罕见。虽然这些患者接受了抗真菌药物治疗，不幸的是,其中一半显示出次优反应。
方法：一名45岁有免疫能力的男性因咳嗽入院，黄色痰,呼吸困难持续5个月。胸部计算机断层扫描显示右主支气管肿块伴有右下叶肺不张。
方法：支气管内隐球菌病表现为支气管阻塞和肺塌陷。
方法：进行早期硬支气管镜治疗以切除支气管内梗阻，与抗真菌剂结合使用。
结果：患者在1年随访时恢复良好，临床和放射学完全消退。
结论：本病例为梗阻性支气管内隐球菌病早期应用呼吸介入治疗联合抗真菌药物提供了一个很好的例子。
方法：一名45岁有免疫能力的男性因咳嗽入院，黄色痰,呼吸困难持续5个月。胸部计算机断层扫描显示右主支气管肿块伴有右下叶肺不张。
方法：支气管内隐球菌病表现为支气管阻塞和肺塌陷。
方法：进行早期硬支气管镜治疗以切除支气管内梗阻，与抗真菌剂结合使用。
结果：患者在1年随访时恢复良好，临床和放射学完全消退。
结论：本病例为梗阻性支气管内隐球菌病早期应用呼吸介入治疗联合抗真菌药物提供了一个很好的例子。
