{Reference Type}: Review
{Title}: Early respiratory interventional therapy combined with antifungal agent for endobronchial cryptococcosis: A case report and literature review.
{Author}: Li Q;Wen D;Chen Y;Yang L;Li J;Luo S;
{Journal}: Medicine (Baltimore)
{Volume}: 103
{Issue}: 12
{Year}: 2024 Mar 22
{Factor}: 1.817
{DOI}: 10.1097/MD.0000000000037455
{Abstract}: <B>BACKGROUND: </B>Cryptococcosis presenting as endobronchial obstruction and lung collapse is an extremely rare occurrence. While these patients were treated with antifungal agents, unfortunately, half of them showed a suboptimal response.<BR><B>METHODS: </B>A 45-year-old immunocompetent male was admitted to the hospital due to a cough, yellow phlegm, and dyspnea persisting for 5 months. Chest computer tomography revealed a mass in the right main bronchus accompanied by right lower lobe atelectasis.<BR><B>METHODS: </B>Endobronchial cryptococcosis presenting as endobronchial obstruction and lung collapse.<BR><B>METHODS: </B>Early rigid bronchoscopic therapy was performed to resect endobronchial obstruction, which combined with antifungal agent.<BR><B>RESULTS: </B>The patient recovered well with completely clinical and radiologic resolution at 1 year follow-up.<BR><B>CONCLUSIONS: </B>This case provides a good example of successful utilization of the early respiratory interventional therapy combined with antifungal agent in obstructive endobronchial cryptococcosis.