Abstract：
OBJECTIVE: This study aimed to investigate the incidence of enteral nutrition intolerance (ENI) in patients with sepsis and explore potential risk factors.
METHODS: A case-control study was conducted in patients with sepsis who were receiving enteral nutrition (EN) at a tertiary hospital in China. The included patients were divided into the ENI group and the non-ENI group. Univariate and multivariate analyses were performed to identify the risk factors for ENI.
RESULTS: A total of 859 patients were included in the study. Among them, 288 (33.53%) patients experienced symptoms of ENI, including diarrhea, vomiting, bloating, and gastric retention. Logistic regression analysis revealed that the Acute Physiology and Chronic Health Evaluation H (APACHE H) score, thoracocentesis, and usage of cardiotonic drugs (namely, inotropes) were independent predictors of the ENI.
CONCLUSIONS: The incidence of ENI is relatively high in patients with sepsis, especially in those who have higher APACHE H scores, have undergone thoracocentesis, and have received inotropes.
METHODS: A case-control study was conducted in patients with sepsis who were receiving enteral nutrition (EN) at a tertiary hospital in China. The included patients were divided into the ENI group and the non-ENI group. Univariate and multivariate analyses were performed to identify the risk factors for ENI.
RESULTS: A total of 859 patients were included in the study. Among them, 288 (33.53%) patients experienced symptoms of ENI, including diarrhea, vomiting, bloating, and gastric retention. Logistic regression analysis revealed that the Acute Physiology and Chronic Health Evaluation H (APACHE H) score, thoracocentesis, and usage of cardiotonic drugs (namely, inotropes) were independent predictors of the ENI.
CONCLUSIONS: The incidence of ENI is relatively high in patients with sepsis, especially in those who have higher APACHE H scores, have undergone thoracocentesis, and have received inotropes.
摘要：
目的：本研究旨在调查脓毒症患者肠内营养不耐受（ENI）的发生率并探讨潜在的危险因素。
方法：在中国一家三级医院接受肠内营养（EN）的脓毒症患者中进行了病例对照研究。将纳入的患者分为ENI组和非ENI组。进行单变量和多变量分析以确定ENI的危险因素。
结果：本研究共纳入859例患者。其中,288例（33.53%）患者出现ENI症状，包括腹泻,呕吐,腹胀,和胃潴留。Logistic回归分析显示,急性生理和慢性健康评价H(APACHEH)评分,胸腔穿刺术,和强心药的使用(即，Inotropes）是ENI的独立预测因子。
结论：脓毒症患者的ENI发生率相对较高，尤其是那些APACHEH分数较高的人，做了胸腔穿刺术,并收到了直角肌。
方法：在中国一家三级医院接受肠内营养（EN）的脓毒症患者中进行了病例对照研究。将纳入的患者分为ENI组和非ENI组。进行单变量和多变量分析以确定ENI的危险因素。
结果：本研究共纳入859例患者。其中,288例（33.53%）患者出现ENI症状，包括腹泻,呕吐,腹胀,和胃潴留。Logistic回归分析显示,急性生理和慢性健康评价H(APACHEH)评分,胸腔穿刺术,和强心药的使用(即，Inotropes）是ENI的独立预测因子。
结论：脓毒症患者的ENI发生率相对较高，尤其是那些APACHEH分数较高的人，做了胸腔穿刺术,并收到了直角肌。
