%0 Journal Article
%T Risk Factors of Enternal Nutrition Intolerance in Septic Patients: A Case-control Study.
%A Wang LZ
%A Xiang Y
%A Li Q
%A Zhu YR
%A Fang J
%A Lu XD
%A Zhang ZC
%J Curr Med Sci
%V 44
%N 2
%D 2024 Apr 22
%M 38517677
%F 2.64
%R 10.1007/s11596-024-2849-3
%X <B>OBJECTIVE: </B>This study aimed to investigate the incidence of enteral nutrition intolerance (ENI) in patients with sepsis and explore potential risk factors.<BR><B>METHODS: </B>A case-control study was conducted in patients with sepsis who were receiving enteral nutrition (EN) at a tertiary hospital in China. The included patients were divided into the ENI group and the non-ENI group. Univariate and multivariate analyses were performed to identify the risk factors for ENI.<BR><B>RESULTS: </B>A total of 859 patients were included in the study. Among them, 288 (33.53%) patients experienced symptoms of ENI, including diarrhea, vomiting, bloating, and gastric retention. Logistic regression analysis revealed that the Acute Physiology and Chronic Health Evaluation H (APACHE H) score, thoracocentesis, and usage of cardiotonic drugs (namely, inotropes) were independent predictors of the ENI.<BR><B>CONCLUSIONS: </B>The incidence of ENI is relatively high in patients with sepsis, especially in those who have higher APACHE H scores, have undergone thoracocentesis, and have received inotropes.