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Abstract：
OBJECTIVE: We aim to evaluate the efficacy of CT-guided percutaneous radiofrequency ablation (RFA) and surgical treatment in osteoid osteoma (OO) treated at the Medical University of Graz.
METHODS: In a single-institution study, we analysed data from January 2005 to January 2021 of patients with histological/radiological diagnosis of OO. CT and MRI scans were reviewed for typical findings. Means (with SD) and medians (with IQR) were reported for normally and non-normally distributed variables. Differences between groups were assessed using chi-squared tests and t-tests.
RESULTS: One hundred nineteen patients (mean age: 21.6 ± 10.9 years; 63.9% males) with confirmed OO were retrospectively evaluated. 73 and 43 patients underwent RFA and surgery, respectively. In three cases, RFA combined with surgery was performed. Pre-intervention, 103 patients (88.8%) had undergone CT, and 101 had an MRI (87.1%). The nidus was confirmed in 82.5% of cases with CTs (85/103) and 63.4% with MRIs (64/101). The majority of nidi were located cortically (n = 96; 82.8%), most frequently in the femur (38 patients, 33.3%) with a median size of 8.0 mm (IQR: 5.0-12.0 mm). Median symptom duration before treatment was 6.0 (IQR: 4.0-13.0) months. The complication rate was 12.1% (14/116; 15.1% RFA vs. 7.0% surgery; p = 0.196). In total, 11.2% of patients had persistent symptoms after one week with clinical success rates of RFA and surgery, 86.3% and 90.7% (p = 0.647), respectively.
CONCLUSIONS: Compared to surgical treatment, CT-guided percutaneous RFA is a safe, minimally invasive, reliable, and efficient treatment option for OO.
UNASSIGNED: This article critically assesses the diagnosis and treatment of osteoid osteoma, emphasising accurate imaging, and detailing a non-invasive option for effective management.
CONCLUSIONS: • This study analyses 116 cases of OO at one institution, focusing on symptom persistence, recurrence in short-term follow-up, and complications in two study groups. • Surgery showed higher, though not statistically significant, success despite comparable symptom persistence; CT displayed typical OO features more than MRI, regardless of the intramedullary, cortical and subperiosteal location as well as the site of the affected bone. • CT-guided RFA is an effective therapeutic alternative for OO compared to surgical intervention. In case of atypical OO appearance, RFA is not the first-line treatment.
METHODS: In a single-institution study, we analysed data from January 2005 to January 2021 of patients with histological/radiological diagnosis of OO. CT and MRI scans were reviewed for typical findings. Means (with SD) and medians (with IQR) were reported for normally and non-normally distributed variables. Differences between groups were assessed using chi-squared tests and t-tests.
RESULTS: One hundred nineteen patients (mean age: 21.6 ± 10.9 years; 63.9% males) with confirmed OO were retrospectively evaluated. 73 and 43 patients underwent RFA and surgery, respectively. In three cases, RFA combined with surgery was performed. Pre-intervention, 103 patients (88.8%) had undergone CT, and 101 had an MRI (87.1%). The nidus was confirmed in 82.5% of cases with CTs (85/103) and 63.4% with MRIs (64/101). The majority of nidi were located cortically (n = 96; 82.8%), most frequently in the femur (38 patients, 33.3%) with a median size of 8.0 mm (IQR: 5.0-12.0 mm). Median symptom duration before treatment was 6.0 (IQR: 4.0-13.0) months. The complication rate was 12.1% (14/116; 15.1% RFA vs. 7.0% surgery; p = 0.196). In total, 11.2% of patients had persistent symptoms after one week with clinical success rates of RFA and surgery, 86.3% and 90.7% (p = 0.647), respectively.
CONCLUSIONS: Compared to surgical treatment, CT-guided percutaneous RFA is a safe, minimally invasive, reliable, and efficient treatment option for OO.
UNASSIGNED: This article critically assesses the diagnosis and treatment of osteoid osteoma, emphasising accurate imaging, and detailing a non-invasive option for effective management.
CONCLUSIONS: • This study analyses 116 cases of OO at one institution, focusing on symptom persistence, recurrence in short-term follow-up, and complications in two study groups. • Surgery showed higher, though not statistically significant, success despite comparable symptom persistence; CT displayed typical OO features more than MRI, regardless of the intramedullary, cortical and subperiosteal location as well as the site of the affected bone. • CT-guided RFA is an effective therapeutic alternative for OO compared to surgical intervention. In case of atypical OO appearance, RFA is not the first-line treatment.
摘要：
目的：我们旨在评估在格拉茨医科大学治疗的骨样骨瘤（OO）的CT引导下经皮射频消融（RFA）和手术治疗的疗效。
方法：在单机构研究中，我们分析了2005年1月至2021年1月组织学/放射学诊断为OO的患者的数据.对CT和MRI扫描的典型发现进行了回顾。报告了正态分布和非正态分布变量的平均值（带有SD）和中位数（带有IQR）。使用卡方检验和t检验评估组间差异。
结果：回顾性评估了119例确诊OO的患者（平均年龄：21.6±10.9岁；63.9％为男性）。73和43例患者接受了RFA和手术，分别。在三种情况下，进行RFA联合手术。干预前,103例（88.8%）患者接受了CT检查，101人进行了MRI（87.1%）。在82.5%的CT病例(85/103)和63.4%的MRI病例(64/101)中证实了病灶。大部分nidi位于皮质（n=96；82.8％），最常见的是股骨(38例患者，33.3%），中位尺寸为8.0毫米（IQR：5.0-12.0毫米）。治疗前症状持续时间中位数为6.0(IQR:4.0-13.0)个月。并发症发生率为12.1%(14/116;15.1%RFAvs.7.0%手术；p=0.196）。总的来说,11.2％的患者在一周后出现持续症状，RFA和手术的临床成功率。86.3%和90.7%(p=0.647)，分别。
结论：与手术治疗相比，CT引导下经皮RFA是一种安全、微创,可靠,和有效的OO治疗选择。
■本文严格评估骨样骨瘤的诊断和治疗，强调准确的成像，并详细说明有效管理的非侵入性选项。
结论：•本研究分析了一个机构的116例OO病例，专注于症状的持久性，短期随访复发，两个研究组的并发症。•手术显示更高，虽然没有统计学意义，尽管症状持续存在，但成功；CT比MRI更显示典型的OO特征，不管髓内,皮质和骨膜下位置以及受影响骨的部位。•与手术干预相比，CT引导的RFA是OO的有效治疗替代方案。在非典型OO外观的情况下，RFA不是一线治疗。
方法：在单机构研究中，我们分析了2005年1月至2021年1月组织学/放射学诊断为OO的患者的数据.对CT和MRI扫描的典型发现进行了回顾。报告了正态分布和非正态分布变量的平均值（带有SD）和中位数（带有IQR）。使用卡方检验和t检验评估组间差异。
结果：回顾性评估了119例确诊OO的患者（平均年龄：21.6±10.9岁；63.9％为男性）。73和43例患者接受了RFA和手术，分别。在三种情况下，进行RFA联合手术。干预前,103例（88.8%）患者接受了CT检查，101人进行了MRI（87.1%）。在82.5%的CT病例(85/103)和63.4%的MRI病例(64/101)中证实了病灶。大部分nidi位于皮质（n=96；82.8％），最常见的是股骨(38例患者，33.3%），中位尺寸为8.0毫米（IQR：5.0-12.0毫米）。治疗前症状持续时间中位数为6.0(IQR:4.0-13.0)个月。并发症发生率为12.1%(14/116;15.1%RFAvs.7.0%手术；p=0.196）。总的来说,11.2％的患者在一周后出现持续症状，RFA和手术的临床成功率。86.3%和90.7%(p=0.647)，分别。
结论：与手术治疗相比，CT引导下经皮RFA是一种安全、微创,可靠,和有效的OO治疗选择。
■本文严格评估骨样骨瘤的诊断和治疗，强调准确的成像，并详细说明有效管理的非侵入性选项。
结论：•本研究分析了一个机构的116例OO病例，专注于症状的持久性，短期随访复发，两个研究组的并发症。•手术显示更高，虽然没有统计学意义，尽管症状持续存在，但成功；CT比MRI更显示典型的OO特征，不管髓内,皮质和骨膜下位置以及受影响骨的部位。•与手术干预相比，CT引导的RFA是OO的有效治疗替代方案。在非典型OO外观的情况下，RFA不是一线治疗。
