关键词: Aortic regurgitation Cardiac magnetic resonance Myocardial fibrosis Myocardial remodeling Phase-contrast imaging

Mesh : Humans Aortic Valve Insufficiency / diagnostic imaging physiopathology Ventricular Remodeling Fibrosis / diagnostic imaging Severity of Illness Index Magnetic Resonance Imaging, Cine / methods Magnetic Resonance Imaging / methods Reproducibility of Results Contrast Media

来  源:   DOI:10.1007/s11886-024-02044-3

Abstract:
OBJECTIVE: Cardiac magnetic resonance (CMR) is emerging as a valuable imaging modality for the assessment of aortic regurgitation (AR). In this review, we discuss the assessment of AR severity, left ventricular (LV) remodeling, and tissue characterization by CMR while highlighting the latest studies and addressing future research needs.
RESULTS: Recent studies have further established CMR-based thresholds of AR severity and LV remodeling that are associated with adverse clinical outcomes, and lower than current guideline criteria. In addition, tissue profiling with late gadolinium enhancement (LGE) and extracellular volume (ECV) quantification can reliably assess adverse myocardial tissue remodeling which is also associated with adverse outcomes. The strengths and reproducibility of CMR in evaluating ventricular volumes, tissue characteristics, and regurgitation severity position it as an excellent modality in evaluating and following AR patients. Advanced CMR techniques for the detection of tissue remodeling have shown significant potential and merit further investigation.
摘要:
目的:心脏磁共振(CMR)正在成为评估主动脉瓣反流(AR)的一种有价值的成像方式。在这次审查中,我们讨论了AR严重程度的评估,左心室(LV)重塑,和组织表征CMR,同时突出最新的研究和满足未来的研究需求。
结果:最近的研究进一步确立了基于CMR的AR严重程度阈值和与不良临床结局相关的LV重塑阈值。低于目前的指导标准。此外,采用晚期钆增强(LGE)和细胞外体积(ECV)定量的组织谱分析可以可靠地评估不良心肌组织重塑,这也与不良结局相关.CMR在评估心室容积方面的优势和可重复性,组织特征,和反流严重程度将其定位为评估和跟踪AR患者的极好方式。用于检测组织重塑的先进CMR技术已显示出巨大的潜力,值得进一步研究。
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