METHODS: Epiflex (n = 3) was evaluated in comparison to palatal tissue from body donors (n = 3). Key metrics, such as elongation and tear resistance, were quantified. Both graft types underwent histological analysis and scanning electron microscopy. Additionally, the healing properties of Epiflex were assessed using a Chorioallantoic Membrane (CAM) Assay.
RESULTS: Biomechanically, Epiflex (mean = 116.01 N) demonstrated the ability to withstand greater forces (p = 0.013) than human palatal tissue (mean = 12.58 N). When comparing the elongation, no significant difference was measured (ASG mean = 9.93 mm, EF mean = 9.7 mm). Histologically, Epiflex exhibited a loosely connected network of collagen fibers with a dense upper layer. The CAM Assay indicated efficient revascularization.
CONCLUSIONS: Epiflex appears to be a viable option for soft tissue augmentation, particularly appealing to patient groups who avoid all or specific animal-derived products due to ethical or religious reasons.
方法:将Epiflex(n=3)与来自身体供体(n=3)的腭组织进行比较。关键指标,如伸长率和抗撕裂性,被量化了。两种移植物都进行了组织学分析和扫描电子显微镜检查。此外,使用绒毛尿囊膜(CAM)测定评估Epiflex的愈合特性。
结果:生物力学,Epiflex(平均值=116.01N)显示出比人pal组织(平均值=12.58N)承受更大的力(p=0.013)的能力。比较伸长率时,测量无显著差异(ASG平均值=9.93mm,EF平均值=9.7mm)。组织学上,Epiflex表现出松散连接的胶原纤维网络,上层致密。CAM测定表明有效的血运重建。
结论:Epiflex似乎是软组织增强的可行选择,特别吸引那些由于道德或宗教原因而避免使用所有或特定动物衍生产品的患者群体。