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Abstract：
OBJECTIVE: To compare stent-related symptoms (SRS) in patients with double J (DJ) undergoing substitution with a pigtail suture stent (PSS) after ureteroscopy (URS), through the Ureteral Stent Symptom Questionnaire (USSQ).
METHODS: Patients with DJ undergoing URS for stone treatment were enrolled in this prospective multicenter longitudinal study. The USSQ was submitted thrice: 2 weeks after DJ, 2 weeks after PSS and 4 weeks after PSS removal (baseline).
METHODS: to compare Urinary Symptom Index Score and the rate of patients with pain 2 weeks after DJ and PSS. Secondary endpoints: to compare other USSQ scores and single answers 2 weeks after DJ and PSS, and DJ and PSS USSQ scores with baseline.
RESULTS: 93 patients were enrolled. 2 weeks Urinary Symptom Index Score (p < 0.001) and the percentage of patients complaining of pain (60.2% vs 88.2%, p < 0.001) were significantly in favour of PSS compared to DJ. 2 weeks scores were significantly improved with PSS compared to DJ: Pain Index (p < 0.001), VAS (p < 0.001), General Health Index (p < 0.001) and Work Performance Index (p < 0.001). All urinary symptoms were significantly decreased with PSS, including renal pain during micturition and pain interfering with life. Pain Index Score (p = 0.622) and VAS (p = 0.169) were comparable to baseline with PSS, while differed with DJ.
CONCLUSIONS: Patients undergoing DJ substitution with PSS after URS report a significant decrease of SRS. Urologists may consider positioning PSS after URS in pre-stented patients to reduce the impact of SRS.
METHODS: Patients with DJ undergoing URS for stone treatment were enrolled in this prospective multicenter longitudinal study. The USSQ was submitted thrice: 2 weeks after DJ, 2 weeks after PSS and 4 weeks after PSS removal (baseline).
METHODS: to compare Urinary Symptom Index Score and the rate of patients with pain 2 weeks after DJ and PSS. Secondary endpoints: to compare other USSQ scores and single answers 2 weeks after DJ and PSS, and DJ and PSS USSQ scores with baseline.
RESULTS: 93 patients were enrolled. 2 weeks Urinary Symptom Index Score (p < 0.001) and the percentage of patients complaining of pain (60.2% vs 88.2%, p < 0.001) were significantly in favour of PSS compared to DJ. 2 weeks scores were significantly improved with PSS compared to DJ: Pain Index (p < 0.001), VAS (p < 0.001), General Health Index (p < 0.001) and Work Performance Index (p < 0.001). All urinary symptoms were significantly decreased with PSS, including renal pain during micturition and pain interfering with life. Pain Index Score (p = 0.622) and VAS (p = 0.169) were comparable to baseline with PSS, while differed with DJ.
CONCLUSIONS: Patients undergoing DJ substitution with PSS after URS report a significant decrease of SRS. Urologists may consider positioning PSS after URS in pre-stented patients to reduce the impact of SRS.
摘要：
目的：比较输尿管镜检查（URS）后接受尾纤缝合支架（PSS）置换的双J（DJ）患者的支架相关症状（SRS），通过输尿管支架症状问卷（USSQ）。
方法：这项前瞻性多中心纵向研究纳入了接受URS治疗的DJ患者。USSQ提交三次：DJ后2周，PSS去除后2周和PSS去除后4周(基线)。
方法：比较泌尿系统症状指数评分和患者术后2周疼痛的发生率。次要终点：比较DJ和PSS后2周的其他USSQ分数和单个答案，DJ和PSSUSSQ评分与基线。
结果：纳入93例患者。2周排尿症状指数评分（p<0.001）和抱怨疼痛的患者百分比（60.2％vs88.2％，与DJ相比，p<0.001）显着有利于PSS。与DJ相比，PSS的2周评分显着提高：疼痛指数（p<0.001），VAS（p<0.001），一般健康指数(p<0.001)和工作绩效指数(p<0.001)。所有尿路症状均显著降低PSS,包括排尿时的肾脏疼痛和影响生活的疼痛。疼痛指数评分（p=0.622）和VAS（p=0.169）与PSS基线相当，与DJ不同。
结论：在URS后接受PSS替换DJ的患者报告SRS显著降低。泌尿科医师可能会考虑在植入前支架的患者中在URS后定位PSS，以减少SRS的影响。
方法：这项前瞻性多中心纵向研究纳入了接受URS治疗的DJ患者。USSQ提交三次：DJ后2周，PSS去除后2周和PSS去除后4周(基线)。
方法：比较泌尿系统症状指数评分和患者术后2周疼痛的发生率。次要终点：比较DJ和PSS后2周的其他USSQ分数和单个答案，DJ和PSSUSSQ评分与基线。
结果：纳入93例患者。2周排尿症状指数评分（p<0.001）和抱怨疼痛的患者百分比（60.2％vs88.2％，与DJ相比，p<0.001）显着有利于PSS。与DJ相比，PSS的2周评分显着提高：疼痛指数（p<0.001），VAS（p<0.001），一般健康指数(p<0.001)和工作绩效指数(p<0.001)。所有尿路症状均显著降低PSS,包括排尿时的肾脏疼痛和影响生活的疼痛。疼痛指数评分（p=0.622）和VAS（p=0.169）与PSS基线相当，与DJ不同。
结论：在URS后接受PSS替换DJ的患者报告SRS显著降低。泌尿科医师可能会考虑在植入前支架的患者中在URS后定位PSS，以减少SRS的影响。
