{Reference Type}: Clinical Trial
{Title}: Patients undergoing double J substitution with a pigtail suture stent report a significant decrease of stent-related symptoms. Results from a prospective multicenter longitudinal trial.
{Author}: Bosio A;Ferretti S;Alessandria E;Vitiello F;Vercelli E;Campobasso D;Micai L;Gozzo C;Bertello G;Guarino GG;Alice C;Bisconti A;Fop F;Gontero P;
{Journal}: World J Urol
{Volume}: 42
{Issue}: 1
{Year}: 2024 Mar 22
{Factor}: 3.661
{DOI}: 10.1007/s00345-024-04879-5
{Abstract}: <B>OBJECTIVE: </B>To compare stent-related symptoms (SRS) in patients with double J (DJ) undergoing substitution with a pigtail suture stent (PSS) after ureteroscopy (URS), through the Ureteral Stent Symptom Questionnaire (USSQ).<BR><B>METHODS: </B>Patients with DJ undergoing URS for stone treatment were enrolled in this prospective multicenter longitudinal study. The USSQ was submitted thrice: 2 weeks after DJ, 2 weeks after PSS and 4 weeks after PSS removal (baseline).<BR><B>METHODS: </B>to compare Urinary Symptom Index Score and the rate of patients with pain 2 weeks after DJ and PSS. Secondary endpoints: to compare other USSQ scores and single answers 2 weeks after DJ and PSS, and DJ and PSS USSQ scores with baseline.<BR><B>RESULTS: </B>93 patients were enrolled. 2 weeks Urinary Symptom Index Score (p < 0.001) and the percentage of patients complaining of pain (60.2% vs 88.2%, p < 0.001) were significantly in favour of PSS compared to DJ. 2 weeks scores were significantly improved with PSS compared to DJ: Pain Index (p < 0.001), VAS (p < 0.001), General Health Index (p < 0.001) and Work Performance Index (p < 0.001). All urinary symptoms were significantly decreased with PSS, including renal pain during micturition and pain interfering with life. Pain Index Score (p = 0.622) and VAS (p = 0.169) were comparable to baseline with PSS, while differed with DJ.<BR><B>CONCLUSIONS: </B>Patients undergoing DJ substitution with PSS after URS report a significant decrease of SRS. Urologists may consider positioning PSS after URS in pre-stented patients to reduce the impact of SRS.