Abstract：
OBJECTIVE: This study aimed to address the critical need for more accurate growth reference charts for preterm infants, with a particular focus on low- and very low-birth-weight infants.
METHODS: The subjects were recruited at a single tertiary centre. The cohort comprised singleton and twin infants born before 37 weeks of gestation, with data collected from 2000 to 2016. Standardised measurements of body parameters were recorded in this mixed longitudinal survey. LMS method was utilised for data analysis. Statistical analysis was performed using SPSS Statistics Version 21. The validation with another new cohort was executed.
RESULTS: A total of 1781 infants (52.5% boys) met the inclusion criteria. The median gestational age at birth was 30 weeks, with a median birth weight of 1350 grams. The main findings included the construction of ImaGrow charts for low- and very low-birth-weight infants and significant differences in growth trajectories compared to Fenton+WHO charts.
CONCLUSIONS: Our comprehensive growth references, ImaGrow, are based on a long-term auxological assessment of preterm infants and differ from charts derived from size-at-birth standards or charts for term babies. These charts have significant implications for clinical practice in monitoring and assessing the growth of preterm infants.
METHODS: The subjects were recruited at a single tertiary centre. The cohort comprised singleton and twin infants born before 37 weeks of gestation, with data collected from 2000 to 2016. Standardised measurements of body parameters were recorded in this mixed longitudinal survey. LMS method was utilised for data analysis. Statistical analysis was performed using SPSS Statistics Version 21. The validation with another new cohort was executed.
RESULTS: A total of 1781 infants (52.5% boys) met the inclusion criteria. The median gestational age at birth was 30 weeks, with a median birth weight of 1350 grams. The main findings included the construction of ImaGrow charts for low- and very low-birth-weight infants and significant differences in growth trajectories compared to Fenton+WHO charts.
CONCLUSIONS: Our comprehensive growth references, ImaGrow, are based on a long-term auxological assessment of preterm infants and differ from charts derived from size-at-birth standards or charts for term babies. These charts have significant implications for clinical practice in monitoring and assessing the growth of preterm infants.
摘要：
目的：本研究旨在解决早产儿对更准确的生长参考图的迫切需要，特别关注低和极低出生体重的婴儿。
方法：受试者在一个三级中心招募。该队列包括妊娠37周前出生的单胎和双胎婴儿，从2000年到2016年收集的数据。在此混合纵向调查中记录了身体参数的标准化测量。采用LMS方法进行数据分析。使用SPSS统计版本21进行统计分析。执行了与另一个新队列的验证。
结果：共有1781名婴儿（52.5%的男孩）符合纳入标准。出生时的中位胎龄为30周，出生体重中位数为1350克。主要发现包括构建低出生体重和极低出生体重婴儿的ImaGrow图表，以及与FentonWHO图表相比，生长轨迹存在显着差异。
结论：我们的综合增长参考，ImaGrow,基于对早产儿的长期营养评估，与从出生时大小标准或足月婴儿图表得出的图表不同。这些图表对监测和评估早产儿生长的临床实践具有重要意义。
方法：受试者在一个三级中心招募。该队列包括妊娠37周前出生的单胎和双胎婴儿，从2000年到2016年收集的数据。在此混合纵向调查中记录了身体参数的标准化测量。采用LMS方法进行数据分析。使用SPSS统计版本21进行统计分析。执行了与另一个新队列的验证。
结果：共有1781名婴儿（52.5%的男孩）符合纳入标准。出生时的中位胎龄为30周，出生体重中位数为1350克。主要发现包括构建低出生体重和极低出生体重婴儿的ImaGrow图表，以及与FentonWHO图表相比，生长轨迹存在显着差异。
结论：我们的综合增长参考，ImaGrow,基于对早产儿的长期营养评估，与从出生时大小标准或足月婴儿图表得出的图表不同。这些图表对监测和评估早产儿生长的临床实践具有重要意义。
