关键词: ESKAPE México Sonora antibiotic resistance clinical isolates

Mesh : Acinetobacter baumannii Anti-Bacterial Agents / pharmacology therapeutic use Cross-Sectional Studies Drug Resistance, Multiple, Bacterial Klebsiella pneumoniae Mexico Humans

来  源:   DOI:10.3389/fcimb.2024.1348093   PDF(Pubmed)

Abstract:
UNASSIGNED: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. are microorganisms referred as the ESKAPE group pathogens. These microorganisms have generated great concern in health institutions around the world since most of them have resistance to multiple antibiotics and cause most infections associated with healthcare, as well as community infections. The aim of this study was the analysis of antibiotic resistance in microorganisms of the ESKAPE group, recovered from clinical samples in 11 health institutions from Hermosillo and Ciudad Obregón in the State of Sonora, México, during the period from 2019 to 2020.
UNASSIGNED: A cross-sectional, descriptive, observational, and temporality epidemiological study was carried out. A comparative and statistical analysis of antibiotic resistance was carried out using the chi-square test, and small values were analyzed using Fisher\'s exact test p ≤ 0.05.
UNASSIGNED: All the ESKAPE group microorganisms showed significant differences in antibiotic resistance percentages between both cities. High resistance percentages for some antibiotics, like cephalosporins and ciprofloxacin were detected for Klebsiella pneumoniae and Acinetobacter baumannii.
摘要:
屎肠球菌,金黄色葡萄球菌,肺炎克雷伯菌,鲍曼不动杆菌,铜绿假单胞菌,和肠杆菌。是被称为ESKAPE组病原体的微生物。这些微生物在世界各地的卫生机构中引起了极大的关注,因为它们中的大多数对多种抗生素具有耐药性,并导致大多数与医疗保健相关的感染。以及社区感染。这项研究的目的是分析ESKAPE组微生物中的抗生素抗性,从索诺拉州Hermosillo和ObregónCiudad的11个卫生机构的临床样本中回收,墨西哥,2019年至2020年期间。
横截面,描述性,描述性观察,并进行了时间性流行病学研究。使用卡方检验对抗生素耐药性进行了比较和统计分析,和小值使用Fisher精确检验p≤0.05进行分析。
所有ESKAPE组微生物在两个城市之间的抗生素抗性百分比均存在显着差异。一些抗生素的高耐药率,如头孢菌素和环丙沙星检测肺炎克雷伯菌和鲍曼不动杆菌。
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