关键词： Dynamic trajectory radiotherapy Head and neck cancer NTCP Treatment planning VMAT

Mesh ： Humans Head and Neck Neoplasms / radiotherapy Radiotherapy, Intensity-Modulated / adverse effects methods Organs at Risk / radiation effects Radiotherapy Dosage Male Radiotherapy Planning, Computer-Assisted / methods Female Middle Aged Deglutition Disorders / etiology Aged Xerostomia / etiology

来  源：   DOI：10.1016/j.radonc.2024.110237

Abstract：
We compared dynamic trajectory radiotherapy (DTRT) to state-of-the-art volumetric modulated arc therapy (VMAT) for 46 head and neck cancer cases. DTRT had lower dose to salivary glands and swallowing structure, resulting in lower predicted xerostomia and dysphagia compared to VMAT. DTRT is deliverable on C-arm linacs with high dosimetric accuracy.
摘要：
我们比较了46例头颈部癌症病例的动态轨迹放射治疗（DTRT）与最先进的体积调制电弧治疗（VMAT）。DTRT对唾液腺和吞咽结构的剂量较低，与VMAT相比，预测口干症和吞咽困难较低。DTRT可在C臂直线加速器上交付，具有高剂量精度。
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