PDF(Pubmed)
Abstract：
Pneumatosis intestinalis (PI) is a rare disease, and there are many theories about its pathogenesis. Hepatic portal venous gas (HPVG), is thought to occur secondary to intramural intestinal gas emboli migrating through the portal venous system via the mesenteric veins. PI accompanied by HPVG is usually a sign of bowel ischaemia and is associated with a high mortality rate. We report here, a patient with liver metastases from colorectal cancer who developed PI followed by HPVG after treatment with 5-Fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6). Timely attention and management of gastrointestinal symptoms following chemotherapy are essential in the treatment of this type of patient.
摘要：
肠源性肺炎(PI)是一种罕见的疾病，关于其发病机理有许多理论。肝门静脉气体（HPVG），被认为是继发于肠系膜静脉通过门静脉系统迁移的肠壁内气体栓子的发生。伴有HPVG的PI通常是肠缺血的征兆，并且与高死亡率有关。我们在这里报道，一名患有结直肠癌肝转移的患者，在用5-氟尿嘧啶治疗后出现PI，随后出现HPVG，亚叶酸,和奥沙利铂（mFOLFOX6）。化疗后及时注意和处理胃肠道症状对于治疗此类患者至关重要。
