PDF(Pubmed)
Abstract：
UNASSIGNED: The present systematic review and meta-analysis was done to assess the rate of Toxoplasma gondii (T. gondii) exposure among Iranian healthy blood donors.
UNASSIGNED: We searched four English (PubMed, Scopus, Web of Science, and Science Direct) and two Persian databases (Magiran and SID) as well as Google Scholar as a specialized article search engine using specific keywords for relevant papers from the inception up to November 30, 2023.
UNASSIGNED: In total, 19 studies enrolling 8226 apparently healthy blood donors were examined regarding T. gondii-specific IgG and/or IgM antibodies, among which 2666 [32.9% (95% CI: 25.3%-41.6%)], 168 [1.4% (95% CI: 0.9%-2.1%)], and 83 [1.7% (95% CI: 1.3%-2.1%)] subjects were seropositive regarding IgG, IgM, and both IgG/IgM antibodies, respectively. Five risk factors were significantly associated with T. gondii seroprevalence, including gender (OR = 1.98; 95% CI: 1.52-2.58; P < 0.001), contact with cat (OR = 2.41; 95% CI: 1.70-3.41; P < 0.001), contact with soil (OR = 2.83; 95% CI: 1.07-7.45; P = 0.035), consuming raw/undercooked meat (OR = 1.95; 95% CI: 1.03-3.70; P = 0.039), and raw/unwashed vegetables (OR = 1.70; 95% CI: 1.25-2.31; P = 0.001).
UNASSIGNED: A moderate rate of T. gondii exposure was found in the Iranian blood donors, with the association of several risk factors, including gender, contact with cat, contact with soil, consumption of unwashed vegetables and/or undercooked meat. Still, more studies are recommended regarding T. gondii exposure among blood donors in Iran.
UNASSIGNED: We searched four English (PubMed, Scopus, Web of Science, and Science Direct) and two Persian databases (Magiran and SID) as well as Google Scholar as a specialized article search engine using specific keywords for relevant papers from the inception up to November 30, 2023.
UNASSIGNED: In total, 19 studies enrolling 8226 apparently healthy blood donors were examined regarding T. gondii-specific IgG and/or IgM antibodies, among which 2666 [32.9% (95% CI: 25.3%-41.6%)], 168 [1.4% (95% CI: 0.9%-2.1%)], and 83 [1.7% (95% CI: 1.3%-2.1%)] subjects were seropositive regarding IgG, IgM, and both IgG/IgM antibodies, respectively. Five risk factors were significantly associated with T. gondii seroprevalence, including gender (OR = 1.98; 95% CI: 1.52-2.58; P < 0.001), contact with cat (OR = 2.41; 95% CI: 1.70-3.41; P < 0.001), contact with soil (OR = 2.83; 95% CI: 1.07-7.45; P = 0.035), consuming raw/undercooked meat (OR = 1.95; 95% CI: 1.03-3.70; P = 0.039), and raw/unwashed vegetables (OR = 1.70; 95% CI: 1.25-2.31; P = 0.001).
UNASSIGNED: A moderate rate of T. gondii exposure was found in the Iranian blood donors, with the association of several risk factors, including gender, contact with cat, contact with soil, consumption of unwashed vegetables and/or undercooked meat. Still, more studies are recommended regarding T. gondii exposure among blood donors in Iran.
摘要：
■本系统评价和荟萃分析是为了评估弓形虫(T.gondii）伊朗健康献血者中的暴露。
■我们搜索了四个英文（PubMed，Scopus,WebofScience,和ScienceDirect）和两个波斯语数据库（Magiran和SID）以及GoogleScholar作为专门的文章搜索引擎，从成立之初到2023年11月30日，使用相关论文的特定关键字。
■总共，19项研究招募8226名明显健康的献血者，对弓形虫特异性IgG和/或IgM抗体进行了检查。其中2666[32.9%（95%CI：25.3%-41.6%）]，168[1.4%（95%CI：0.9%-2.1%）]，和83[1.7%（95%CI：1.3%-2.1%）]受试者的IgG血清呈阳性，IgM,和IgG/IgM抗体，分别。五个危险因素与弓形虫血清阳性率显著相关，包括性别(OR=1.98;95%CI:1.52-2.58;P<0.001),与猫接触（OR=2.41；95%CI：1.70-3.41；P<0.001），与土壤接触(OR=2.83；95%CI：1.07-7.45；P=0.035)，食用生/未煮熟的肉（OR=1.95；95％CI：1.03-3.70；P=0.039），生菜/未清洗蔬菜（OR=1.70；95%CI：1.25-2.31；P=0.001）。
■在伊朗献血者中发现了适度的弓形虫暴露率，与几个危险因素的联系，包括性别,与猫接触,与土壤接触,食用未清洗的蔬菜和/或未煮熟的肉。尽管如此，建议对伊朗献血者中弓形虫暴露进行更多研究。
■我们搜索了四个英文（PubMed，Scopus,WebofScience,和ScienceDirect）和两个波斯语数据库（Magiran和SID）以及GoogleScholar作为专门的文章搜索引擎，从成立之初到2023年11月30日，使用相关论文的特定关键字。
■总共，19项研究招募8226名明显健康的献血者，对弓形虫特异性IgG和/或IgM抗体进行了检查。其中2666[32.9%（95%CI：25.3%-41.6%）]，168[1.4%（95%CI：0.9%-2.1%）]，和83[1.7%（95%CI：1.3%-2.1%）]受试者的IgG血清呈阳性，IgM,和IgG/IgM抗体，分别。五个危险因素与弓形虫血清阳性率显著相关，包括性别(OR=1.98;95%CI:1.52-2.58;P<0.001),与猫接触（OR=2.41；95%CI：1.70-3.41；P<0.001），与土壤接触(OR=2.83；95%CI：1.07-7.45；P=0.035)，食用生/未煮熟的肉（OR=1.95；95％CI：1.03-3.70；P=0.039），生菜/未清洗蔬菜（OR=1.70；95%CI：1.25-2.31；P=0.001）。
■在伊朗献血者中发现了适度的弓形虫暴露率，与几个危险因素的联系，包括性别,与猫接触,与土壤接触,食用未清洗的蔬菜和/或未煮熟的肉。尽管如此，建议对伊朗献血者中弓形虫暴露进行更多研究。
