PDF(Pubmed)
Abstract：
UNASSIGNED: Ulcerative colitis (UC) is a recurrent, inflammatory, autoimmune intestinal disease. The dietary calcium to phosphorus (Ca:P) ratio is suggested to affect the inividuals\' normal metabolic and inflammatory pathways. The present study aimed to investigate the association between dietary Ca:P ratio and the odds of developing UC in a case-control format.
UNASSIGNED: The study included sixty-two currently diagnosed UC patients and one hundred twenty-four matched controls, designed as a case-control study. The dietary intakes of the participants were assessed by a food frequency questionnaire (FFQ), and the dietary Ca:P ratio was calculated. The association between tertiles of Ca:P ratio and UC was examined using the logistic regression. P-values <0.05 were considered as significant.
UNASSIGNED: The study sample consisted of participants with an average age of 36.63 ± 12.42 years and a mean body mass index (BMI) of 25.39 ± 3.82 kg/m2. The overall energy-adjusted ratio of Ca:P was 0.74 ± 0.11. In the multivariate model, after adjustment for potential confounders, participants in the third tertile of dietary Ca:P ratio had a lower odds of developing UC compared to the lowest tertlie (OR: 0.34, 95% CI: 0.13-0.87; p = 0.026).
UNASSIGNED: Our results indicate that a higher ratio of dietary Ca:P ratio might be protective against developing UC. However, further studies are warranted to examine this association in various populations.
UNASSIGNED: The study included sixty-two currently diagnosed UC patients and one hundred twenty-four matched controls, designed as a case-control study. The dietary intakes of the participants were assessed by a food frequency questionnaire (FFQ), and the dietary Ca:P ratio was calculated. The association between tertiles of Ca:P ratio and UC was examined using the logistic regression. P-values <0.05 were considered as significant.
UNASSIGNED: The study sample consisted of participants with an average age of 36.63 ± 12.42 years and a mean body mass index (BMI) of 25.39 ± 3.82 kg/m2. The overall energy-adjusted ratio of Ca:P was 0.74 ± 0.11. In the multivariate model, after adjustment for potential confounders, participants in the third tertile of dietary Ca:P ratio had a lower odds of developing UC compared to the lowest tertlie (OR: 0.34, 95% CI: 0.13-0.87; p = 0.026).
UNASSIGNED: Our results indicate that a higher ratio of dietary Ca:P ratio might be protective against developing UC. However, further studies are warranted to examine this association in various populations.
摘要：
■溃疡性结肠炎（UC）是一种复发性，炎症，自身免疫性肠道疾病。建议饮食中钙磷比（Ca：P）会影响个体的正常代谢和炎症途径。本研究旨在以病例对照形式调查饮食Ca：P比与UC发展几率之间的关系。
■该研究包括62名目前诊断为UC的患者和124名匹配的对照，设计为病例对照研究。参与者的饮食摄入量通过食物频率问卷（FFQ）进行评估，并计算了日粮Ca:P比。使用逻辑回归检查了Ca：P比的三元与UC之间的关联。P值<0.05被认为是显著的。
■研究样本包括平均年龄为36.63±12.42岁，平均体重指数（BMI）为25.39±3.82kg/m2的参与者。Ca：P的总能量调节比为0.74±0.11。在多变量模型中，在调整了潜在的混杂因素后，与最低组相比,第3组膳食钙:磷比率的参与者患UC的几率较低(OR:0.34,95%CI:0.13~0.87;p=0.026).
■我们的结果表明，较高的饮食Ca：P比率可能对发展为UC具有保护作用。然而,需要进一步的研究来检查不同人群中的这种关联.
■该研究包括62名目前诊断为UC的患者和124名匹配的对照，设计为病例对照研究。参与者的饮食摄入量通过食物频率问卷（FFQ）进行评估，并计算了日粮Ca:P比。使用逻辑回归检查了Ca：P比的三元与UC之间的关联。P值<0.05被认为是显著的。
■研究样本包括平均年龄为36.63±12.42岁，平均体重指数（BMI）为25.39±3.82kg/m2的参与者。Ca：P的总能量调节比为0.74±0.11。在多变量模型中，在调整了潜在的混杂因素后，与最低组相比,第3组膳食钙:磷比率的参与者患UC的几率较低(OR:0.34,95%CI:0.13~0.87;p=0.026).
■我们的结果表明，较高的饮食Ca：P比率可能对发展为UC具有保护作用。然而,需要进一步的研究来检查不同人群中的这种关联.
